Comparison of isotopic substitution methods for equilibrium and t-jump infrared studies of beta-hairpin peptide conformation.

Laser-induced temperature jump (T-jump) kinetics of relaxation was measured by absorbance of infrared (IR) detection for a set of peptide beta-hairpin, associated with hairpins Trpzip2, but it contains a label isotope single, (13) C to the amide C horizontal Lineo residue the selected both at the center and in the terminal strands of the hairpin. Variation in the behavior of a single labeled peptide compared with those previously reported for the double-la

beled variants. Although a single label does not produce an increase in spectral intensity, as seen to the labeling of cross-strand, IR frequency shift hairpin diagnostic still ongoing. If C horizontal Lineo at the beta-strands of the hairpin (between residues Trp) is labeled, the dynamic behavior of the local fashion similar to the results obtained with the double label in terms of the relaxation time and energy and closely track the kinetics of activation of beta-strand component.

This means that both the property, local secondary structure (change varphi, psi), or cross-strand clutch is activated by the formation of H-bonded strands and loosening with the same kinetic mechanism. Single residue at position terminal label have different behaviors and less able to detect because it overlaps with the component (12) C, in contrast with the double label involving the position, which is enhanced due to coupling. DFT-based spectral simulation using NMR structure of Trpzip2C showed that single-labeled peptides must have a roughly equivalent (12) C band but (13) C mode frequency will vary with the position of the sequence. effective solvent correction using COSMO yield significant changes in frequency but not in relative isotope shift in the spectrum obtained we calculated. The sequence dependency label position is shown to be more discriminatory than the variation thermodynamics kinetics change.

1G Dithiothreitol (DTT)
NAT1066 1G
EUR 63.6

5G Dithiothreitol (DTT)
NAT1068 5G
EUR 183.6

DL-1,4-Dithiothreitol
abx184011-100g 100 g
EUR 526.8

DTT, 1,4-Dithiothreitol, Diaxone free
D0505-001 1g
EUR 111.6

DTT, 1,4-Dithiothreitol, Diaxone free
D0505-005 5g
EUR 148.8

DTT, 1,4-Dithiothreitol, Diaxone free
D0505-010 10g
EUR 217.2

DTT, 1,4-Dithiothreitol, Diaxone free
D0505-050 50g
EUR 604.8

DTT, 1,4-Dithiothreitol, Diaxone free
D0505-100 100g
EUR 842.4

Dithiooxamide
DD1236 5g
EUR 105.94

Dithiooxamide
GX7065-100G 100 g
EUR 418.8

Dithiooxamide
GX7065-25G 25 g
EUR 170.4

Dithiooxamide
GX7065-5G 5 g
EUR 84

Dithiooxamide
GX7065-100 100
EUR 316.4

Dithiooxamide
GX7065-25 25
EUR 110.7

Dithiooxamide
GX7065-5 5
EUR 39.4

Sodium dithionite, 85%
GX8950-1 1
EUR 179.3

2,2'-Dithiodipyridine
GK5006-100G 100 g
EUR 322.8

2,2'-Dithiodipyridine
GK5006-25G 25 g
EUR 122.4

2,2''-Dithiodipyridine
GK5006-100 100
EUR 237.2

2,2''-Dithiodipyridine
GK5006-25 25
EUR 71.1

Dithioerythritol (DTE)
D705322 5g
EUR 127.86

1,4-Dithioerythritol
Q-1220.0025 25.0g
EUR 327.6
Description: Sum Formula: C4H10O2S2; CAS# [6892-68-8]

1,4-Dithioerythritol
Q-1220.0100 100.0g
EUR 907.2
Description: Sum Formula: C4H10O2S2; CAS# [6892-68-8]

1,4-Dithio-DL-threitol
Q-1225.0025 25.0g
EUR 327.6
Description: Sum Formula: C4H10O2S2; CAS# [3483-12-3]

1,4-Dithio-DL-threitol
Q-1225.0100 100.0g
EUR 907.2
Description: Sum Formula: C4H10O2S2; CAS# [3483-12-3]

1,4-Dithioerythritol
GE5960-1 1
EUR 39.4

1,4-Dithioerythritol
GE5960-10 10
EUR 229.3

1,4-Dithioerythritol
GE5960-25 25
EUR 450.8

1,4-Dithioerythritol
GE5960-5 5
EUR 134.4

2,2'-Dithio(Bis)Benzothiazole
abx188164-2kg 2 kg
EUR 410.4

1,4-Dithioerythritol (DTE)
GE5960-10G 10 g
EUR 189.6

1,4-Dithioerythritol (DTE)
GE5960-1G 1 g
EUR 64.8

1,4-Dithioerythritol (DTE)
GE5960-25G 25 g
EUR 322.8

1,4-Dithioerythritol (DTE)
GE5960-5G 5 g
EUR 132

2,2'-Dithiobisbenzanilide
20-abx182953
  • EUR 427.20
  • EUR 292.80
  • EUR 828.00
  • 100 g
  • 25 g
  • 500 g

2,2'-Dithiobis(pyridine-N-oxide)
20-abx182952
  • EUR 260.40
  • EUR 1028.40
  • EUR 410.40
  • 1 g
  • 25 g
  • 5 g

5,5'-Dithiobis(2-nitrobenzoic acid)
20-abx183655
  • EUR 944.40
  • EUR 460.80
  • EUR 260.40
  • 100 g
  • 25 g
  • 5 g

5, 5′-Dithiobis (2-nitrobenzoic acid)
abx082091-1g 1 g
EUR 226.8

5, 5′-Dithiobis (2-nitrobenzoic acid)
abx082288-1g 1 g
EUR 243.6

5,5''-Dithio-bis(2-nitrobenzoic acid)
GK9458-1 1
EUR 21

5,5''-Dithio-bis(2-nitrobenzoic acid)
GK9458-25 25
EUR 163.2

5,5''-Dithio-bis(2-nitrobenzoic acid)
GK9458-5 5
EUR 43

(DTSP);Dithio-bis-succinimidyl propionate
20-abx185680
  • EUR 410.40
  • EUR 1011.60
  • 1 g
  • 5 g

SVOC Std Tetraethyl dithiopyrophosphate 1000ug/mL in MeOH
RESVOC071 1ML
EUR 86.17

SVOC Std Tetraethyl dithiopyrophosphate 2000ug/mL in MeOH
RESVOC072 1ML
EUR 103.14

Dithizone
abx188689-1000g 1000 g
EUR 1062

Dithizone
GT8493-10G 10 g
EUR 76.8

Dithizone
GT8493-25G 25 g
EUR 112.8

Dithizone
GT8493-50G 50 g
EUR 174

Dithizone
GT8493-10 10
EUR 34.1

Dithizone
GT8493-25 25
EUR 63.3

Dithizone
GT8493-50 50
EUR 113.8

2-Vinyl-4H-1,3-dithiin
TBZ2042 unit Ask for price

1000 ug/mL Dithianon in LCMS Acetonitrile
LCS-6754 1ML
EUR 375.6

2,5-Dihydroxy-1,4-Dithiane
abx187881-500g 500 g
EUR 343.2

trans-4,5-Dihydroxy-1,2-dithiane
GX9122-1 1
EUR 126.2

trans-4,5-Dihydroxy-1,2-dithiane
GX9122-100 100
EUR 3094.5

trans-4,5-Dihydroxy-1,2-dithiane
GX9122-5 5
EUR 327

DL-Dithiothreitol
B7294-25000 25 g
EUR 358.8

DL-Dithiothreitol/DTT
ADC-P-081 unit Ask for price

DL-Dithiothreitol, 98%
GC3928-5G 5 g
EUR 64.8

DL-Dithiothreitol, 99%
GC1199-100G 100 g
EUR 361.2

DL-Dithiothreitol, 99%
GC1199-10G 10 g
EUR 93.6

DL-Dithiothreitol, 99%
GC1199-25G 25 g
EUR 141.6

DL-Dithiothreitol, 99%
GC1199-50G 50 g
EUR 217.2

DL-Dithiothreitol, 99%
GC1199-5G 5 g
EUR 69.6

DL-Dithiothreitol, 99%
GC1199-10 10
EUR 71.1

DL-Dithiothreitol, 99%
GC1199-100 100
EUR 427.1

DL-Dithiothreitol, 99%
GC1199-25 25
EUR 142.4

DL-Dithiothreitol, 99%
GC1199-5 5
EUR 39.4

DL-Dithiothreitol, 99%
GC1199-50 50
EUR 249.2

DL-Dithiothreitol, 98%
GC3928-10 10
EUR 55.4

DL-Dithiothreitol, 98%
GC3928-100 100
EUR 355.8

DL-Dithiothreitol, 98%
GC3928-25 25
EUR 110.7

DL-Dithiothreitol, 98%
GC3928-5 5
EUR 31.7

DL-Dithiothreitol, 98%
GC3928-50 50
EUR 208

DL-Dithiothreitol/DTT - biotech grade
ADC-P-082 unit Ask for price

DL-Dithiothreitol/DTT - pure grade
ADC-P-083 unit Ask for price

Dithranol
GC2421-10G 10 g
EUR 112.8

Dithranol
GC2421-25G 25 g
EUR 189.6

Dithranol
HY-B0738 100mg
EUR 142.8

Dithranol
GC2421-10 10
EUR 63.3

Dithranol
GC2421-25 25
EUR 126.5

NSC 109555 ditosylate
B7248-10 10 mg
EUR 408

NSC 109555 ditosylate
B7248-50 50 mg
EUR 1531.2

PD 123319 ditrifluoroacetate
A3704-10 10 mg
EUR 250.8
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 ditrifluoroacetate
A3704-25 25 mg
EUR 489.6
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 ditrifluoroacetate
A3704-5 5 mg
EUR 205.2
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 ditrifluoroacetate
A3704-50 50 mg
EUR 787.2
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 (ditrifluoroacetate)
HY-10259A 10mg
EUR 258

BRD 4354 (ditrifluoroacetate)
HY-112719B 100mg
EUR 1176

Recombinant Canine Heartworm Dirofilaria Immitis DIT33 Protein (aa 18-234)
VAng-Cr4614-inquire inquire Ask for price
Description: Canine Heartworm Dirofilaria Immitis Pepsin inhibitor Dit33 (DIT33), recombinant protein.

Ditiocarb sodium
HY-B1637 1g
EUR 142.8

Dityrosine ELISA kit
LF-EK90006 1x96T
EUR 1170

1000ug/mL Ditalimfos in MeOH
S-4827 1ML
EUR 549.6

Rat Dityrosine(DT)ELISA Kit
YLA1549RA-48T 48T
EUR 465

Rat Dityrosine(DT)ELISA Kit
YLA1549RA-96T 96T
EUR 600

Di-tert-butyl adipate
20-abx180726
  • EUR 1462.80
  • EUR 744.00
  • EUR 5004.00
  • 1 g
  • 250 mg
  • 5 g

Dityrosine Antibody
abx444206-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx444207-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx444487-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx444488-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx444768-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx444769-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx445125-100ug 100 ug
EUR 727.2

Dityrosine Antibody
abx445126-100ug 100 ug
EUR 727.2

Ditolylguanidine
B3044-100 100 mg
EUR 132

Ditolylguanidine
B3044-500 500 mg
EUR 296.4

Dityrosine Antibody
abx440274-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx440275-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx440548-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx440549-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx440836-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx440837-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441117-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441118-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441398-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441399-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441679-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441680-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441960-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx441961-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx443083-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx443084-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx443363-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx443364-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx443644-100ug 100 ug
EUR 777.6

Dityrosine Antibody
abx443645-100ug 100 ug
EUR 777.6

Dityrosine Antibody
abx443925-100ug 100 ug
EUR 811.2

Dityrosine Antibody
abx443926-100ug 100 ug
EUR 811.2

Dityrosine Antibody
abx442241-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx442242-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx442522-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx442523-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx442803-100ug 100 ug
EUR 794.4

Dityrosine Antibody
abx442804-100ug 100 ug
EUR 794.4

Ditolylguanidine
HY-14218 10mM/1mL
EUR 135.6

Lapatinib Ditosylate
A3967-100 100 mg
EUR 157.2
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib Ditosylate
A3967-5.1 10 mM (in 1mL DMSO)
EUR 205.2
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib Ditosylate
A3967-50 50 mg
EUR 129.6
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib Ditosylate
A3967-S Evaluation Sample
EUR 97.2
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib (ditosylate)
HY-50898A 500mg
EUR 274.8

Ditryptophenaline
TBP04426 5mg
EUR 2034

2,7-Di-tert-butylpyrene
20-abx186731
  • EUR 1245.60
  • EUR 543.60
  • 25 g
  • 5 g

Vinorelbine ditartrate
A3921-10 10 mg
EUR 177.6
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine ditartrate
A3921-25 25 mg
EUR 282
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine ditartrate
A3921-5.1 10 mM (in 1mL DMSO)
EUR 324
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine ditartrate
A3921-50 50 mg
EUR 448.8
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine (ditartrate)
HY-12053A 10mg
EUR 159.6

Vinorelbine ditartrate
GP5205-10MG 10 mg
EUR 112.8

Vinorelbine ditartrate
GP5205-25MG 25 mg
EUR 170.4

Vinorelbine ditartrate
GP5205-50MG 50 mg
EUR 274.8

Vinorelbine ditartrate
GP5205-5MG 5 mg
EUR 86.4

N,N''-Di-tert-butylthiourea
GW6661-10 10
EUR 214.1

N,N''-Di-tert-butylthiourea
GW6661-50 50
EUR 737

Vinorelbine ditartrate
GP5205-10 10
EUR 63.3

Vinorelbine ditartrate
GP5205-25 25
EUR 110.7

Vinorelbine ditartrate
GP5205-5 5
EUR 41.9

Vinorelbine ditartrate
GP5205-50 50
EUR 197.7

3,5-Di-Tert-Butylcatechol
abx188340-1kg 1 kg
EUR 1980

Di-tert-butyl dicarbonate
GE4403-100G 100 g
EUR 98.4

Di-tert-butyl dicarbonate
GE4403-250G 250 g
EUR 160.8

Di-tert-butyl dicarbonate
GE4403-25G 25 g
EUR 60

Di-tert-butyl dicarbonate
GE4403-500G 500 g
EUR 254.4

Di-tert-butyl dicarbonate
GE4403-100 100
EUR 51.4

Di-tert-butyl dicarbonate
GE4403-25 25
EUR 20.2

Di-tert-butyl dicarbonate
GE4403-250 250
EUR 102.7

Di-tert-butyl dicarbonate
GE4403-500 500
EUR 180

AZ505 ditrifluoroacetate
B1256-10 10 mg
EUR 648
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate
B1256-100 100 mg
EUR 2815.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate
B1256-25 25 mg
EUR 1309.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate
B1256-5 5 mg
EUR 409.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate
B1256-50 50 mg
EUR 1879.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ-505 ditrifluoroacetate
B1883-1 each
EUR 183.6

AZ-505 ditrifluoroacetate
B1883-5 each
EUR 548.4

AZ505 (ditrifluoroacetate)
HY-15226A 50mg
EUR 1695.6

DiTO™-3 [equivalent to TOTO®-3] *5 mM DMSO Solution*
17576 0.2 ml
EUR 222