Comparison of isotopic substitution methods for equilibrium and t-jump infrared studies of beta-hairpin peptide conformation.

Laser-induced temperature jump (T-jump) kinetics of relaxation was measured by absorbance of infrared (IR) detection for a set of peptide beta-hairpin, associated with hairpins Trpzip2, but it contains a label isotope single, (13) C to the amide C horizontal Lineo residue the selected both at the center and in the terminal strands of the hairpin. Variation in the behavior of a single labeled peptide compared with those previously reported for the double-la

beled variants. Although a single label does not produce an increase in spectral intensity, as seen to the labeling of cross-strand, IR frequency shift hairpin diagnostic still ongoing. If C horizontal Lineo at the beta-strands of the hairpin (between residues Trp) is labeled, the dynamic behavior of the local fashion similar to the results obtained with the double label in terms of the relaxation time and energy and closely track the kinetics of activation of beta-strand component.

This means that both the property, local secondary structure (change varphi, psi), or cross-strand clutch is activated by the formation of H-bonded strands and loosening with the same kinetic mechanism. Single residue at position terminal label have different behaviors and less able to detect because it overlaps with the component (12) C, in contrast with the double label involving the position, which is enhanced due to coupling. DFT-based spectral simulation using NMR structure of Trpzip2C showed that single-labeled peptides must have a roughly equivalent (12) C band but (13) C mode frequency will vary with the position of the sequence. effective solvent correction using COSMO yield significant changes in frequency but not in relative isotope shift in the spectrum obtained we calculated. The sequence dependency label position is shown to be more discriminatory than the variation thermodynamics kinetics change.

1G Dithiothreitol (DTT)

NAT1066 1G
EUR 63.6

5G Dithiothreitol (DTT)

NAT1068 5G
EUR 183.6

DL-1,4-Dithiothreitol

abx184011-100g 100 g
EUR 526.8

DTT, 1,4-Dithiothreitol, Diaxone free

D0505-001 1g
EUR 111.6

DTT, 1,4-Dithiothreitol, Diaxone free

D0505-005 5g
EUR 148.8

DTT, 1,4-Dithiothreitol, Diaxone free

D0505-010 10g
EUR 217.2

DTT, 1,4-Dithiothreitol, Diaxone free

D0505-050 50g
EUR 604.8

DTT, 1,4-Dithiothreitol, Diaxone free

D0505-100 100g
EUR 842.4

Dithiooxamide

DD1236 5g
EUR 105.94

Dithiooxamide

GX7065-100G 100 g
EUR 418.8

Dithiooxamide

GX7065-25G 25 g
EUR 170.4

Dithiooxamide

GX7065-5G 5 g
EUR 84

Dithiooxamide

GX7065-100 100
EUR 316.4

Dithiooxamide

GX7065-25 25
EUR 110.7

Dithiooxamide

GX7065-5 5
EUR 39.4

Sodium dithionite, 85%

GX8950-1 1
EUR 179.3

2,2'-Dithiodipyridine

GK5006-100G 100 g
EUR 322.8

2,2'-Dithiodipyridine

GK5006-25G 25 g
EUR 122.4

2,2''-Dithiodipyridine

GK5006-100 100
EUR 237.2

2,2''-Dithiodipyridine

GK5006-25 25
EUR 71.1

Dithioerythritol (DTE)

D705322 5g
EUR 127.86

1,4-Dithioerythritol

Q-1220.0025 25.0g
EUR 327.6
Description: Sum Formula: C4H10O2S2; CAS# [6892-68-8]

1,4-Dithioerythritol

Q-1220.0100 100.0g
EUR 907.2
Description: Sum Formula: C4H10O2S2; CAS# [6892-68-8]

1,4-Dithio-DL-threitol

Q-1225.0025 25.0g
EUR 327.6
Description: Sum Formula: C4H10O2S2; CAS# [3483-12-3]

1,4-Dithio-DL-threitol

Q-1225.0100 100.0g
EUR 907.2
Description: Sum Formula: C4H10O2S2; CAS# [3483-12-3]

1,4-Dithioerythritol

GE5960-1 1
EUR 39.4

1,4-Dithioerythritol

GE5960-10 10
EUR 229.3

1,4-Dithioerythritol

GE5960-25 25
EUR 450.8

1,4-Dithioerythritol

GE5960-5 5
EUR 134.4

2,2'-Dithio(Bis)Benzothiazole

abx188164-2kg 2 kg
EUR 410.4

1,4-Dithioerythritol (DTE)

GE5960-10G 10 g
EUR 189.6

1,4-Dithioerythritol (DTE)

GE5960-1G 1 g
EUR 64.8

1,4-Dithioerythritol (DTE)

GE5960-25G 25 g
EUR 322.8

1,4-Dithioerythritol (DTE)

GE5960-5G 5 g
EUR 132

2,2'-Dithiobisbenzanilide

20-abx182953
  • EUR 427.20
  • EUR 292.80
  • EUR 828.00
  • 100 g
  • 25 g
  • 500 g

2,2'-Dithiobis(pyridine-N-oxide)

20-abx182952
  • EUR 260.40
  • EUR 1028.40
  • EUR 410.40
  • 1 g
  • 25 g
  • 5 g

5,5'-Dithiobis(2-nitrobenzoic acid)

20-abx183655
  • EUR 944.40
  • EUR 460.80
  • EUR 260.40
  • 100 g
  • 25 g
  • 5 g

5, 5′-Dithiobis (2-nitrobenzoic acid)

abx082091-1g 1 g
EUR 226.8

5, 5′-Dithiobis (2-nitrobenzoic acid)

abx082288-1g 1 g
EUR 243.6

5,5''-Dithio-bis(2-nitrobenzoic acid)

GK9458-1 1
EUR 21

5,5''-Dithio-bis(2-nitrobenzoic acid)

GK9458-25 25
EUR 163.2

5,5''-Dithio-bis(2-nitrobenzoic acid)

GK9458-5 5
EUR 43

(DTSP);Dithio-bis-succinimidyl propionate

20-abx185680
  • EUR 410.40
  • EUR 1011.60
  • 1 g
  • 5 g

SVOC Std Tetraethyl dithiopyrophosphate 1000ug/mL in MeOH

RESVOC071 1ML
EUR 86.17

SVOC Std Tetraethyl dithiopyrophosphate 2000ug/mL in MeOH

RESVOC072 1ML
EUR 103.14

Dithizone

abx188689-1000g 1000 g
EUR 1062

Dithizone

GT8493-10G 10 g
EUR 76.8

Dithizone

GT8493-25G 25 g
EUR 112.8

Dithizone

GT8493-50G 50 g
EUR 174

Dithizone

GT8493-10 10
EUR 34.1

Dithizone

GT8493-25 25
EUR 63.3

Dithizone

GT8493-50 50
EUR 113.8

2-Vinyl-4H-1,3-dithiin

TBZ2042 unit Ask for price

1000 ug/mL Dithianon in LCMS Acetonitrile

LCS-6754 1ML
EUR 375.6

2,5-Dihydroxy-1,4-Dithiane

abx187881-500g 500 g
EUR 343.2

trans-4,5-Dihydroxy-1,2-dithiane

GX9122-1 1
EUR 126.2

trans-4,5-Dihydroxy-1,2-dithiane

GX9122-100 100
EUR 3094.5

trans-4,5-Dihydroxy-1,2-dithiane

GX9122-5 5
EUR 327

DL-Dithiothreitol

B7294-25000 25 g
EUR 358.8

DL-Dithiothreitol/DTT

ADC-P-081 unit Ask for price

DL-Dithiothreitol, 98%

GC3928-5G 5 g
EUR 64.8

DL-Dithiothreitol, 99%

GC1199-100G 100 g
EUR 361.2

DL-Dithiothreitol, 99%

GC1199-10G 10 g
EUR 93.6

DL-Dithiothreitol, 99%

GC1199-25G 25 g
EUR 141.6

DL-Dithiothreitol, 99%

GC1199-50G 50 g
EUR 217.2

DL-Dithiothreitol, 99%

GC1199-5G 5 g
EUR 69.6

DL-Dithiothreitol, 99%

GC1199-10 10
EUR 71.1

DL-Dithiothreitol, 99%

GC1199-100 100
EUR 427.1

DL-Dithiothreitol, 99%

GC1199-25 25
EUR 142.4

DL-Dithiothreitol, 99%

GC1199-5 5
EUR 39.4

DL-Dithiothreitol, 99%

GC1199-50 50
EUR 249.2

DL-Dithiothreitol, 98%

GC3928-10 10
EUR 55.4

DL-Dithiothreitol, 98%

GC3928-100 100
EUR 355.8

DL-Dithiothreitol, 98%

GC3928-25 25
EUR 110.7

DL-Dithiothreitol, 98%

GC3928-5 5
EUR 31.7

DL-Dithiothreitol, 98%

GC3928-50 50
EUR 208

DL-Dithiothreitol/DTT - biotech grade

ADC-P-082 unit Ask for price

DL-Dithiothreitol/DTT - pure grade

ADC-P-083 unit Ask for price

Dithranol

GC2421-10G 10 g
EUR 112.8

Dithranol

GC2421-25G 25 g
EUR 189.6

Dithranol

HY-B0738 100mg
EUR 142.8

Dithranol

GC2421-10 10
EUR 63.3

Dithranol

GC2421-25 25
EUR 126.5

NSC 109555 ditosylate

B7248-10 10 mg
EUR 408

NSC 109555 ditosylate

B7248-50 50 mg
EUR 1531.2

PD 123319 ditrifluoroacetate

A3704-10 10 mg
EUR 250.8
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 ditrifluoroacetate

A3704-25 25 mg
EUR 489.6
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 ditrifluoroacetate

A3704-5 5 mg
EUR 205.2
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 ditrifluoroacetate

A3704-50 50 mg
EUR 787.2
Description: Description:IC50 Value: 1.2 ±0.4 mM (Inhibition of adenylyl cyclase elicited by 0.1 microM Ang II) [2]PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist.

PD 123319 (ditrifluoroacetate)

HY-10259A 10mg
EUR 258

BRD 4354 (ditrifluoroacetate)

HY-112719B 100mg
EUR 1176

Recombinant Canine Heartworm Dirofilaria Immitis DIT33 Protein (aa 18-234)

VAng-Cr4614-inquire inquire Ask for price
Description: Canine Heartworm Dirofilaria Immitis Pepsin inhibitor Dit33 (DIT33), recombinant protein.

Ditiocarb sodium

HY-B1637 1g
EUR 142.8

Dityrosine ELISA kit

LF-EK90006 1x96T
EUR 1170

1000ug/mL Ditalimfos in MeOH

S-4827 1ML
EUR 549.6

Rat Dityrosine(DT)ELISA Kit

YLA1549RA-48T 48T
EUR 465

Rat Dityrosine(DT)ELISA Kit

YLA1549RA-96T 96T
EUR 600

Di-tert-butyl adipate

20-abx180726
  • EUR 1462.80
  • EUR 744.00
  • EUR 5004.00
  • 1 g
  • 250 mg
  • 5 g

Dityrosine Antibody

abx444206-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx444207-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx444487-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx444488-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx444768-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx444769-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx445125-100ug 100 ug
EUR 727.2

Dityrosine Antibody

abx445126-100ug 100 ug
EUR 727.2

Ditolylguanidine

B3044-100 100 mg
EUR 132

Ditolylguanidine

B3044-500 500 mg
EUR 296.4

Dityrosine Antibody

abx440274-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx440275-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx440548-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx440549-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx440836-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx440837-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441117-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441118-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441398-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441399-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441679-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441680-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441960-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx441961-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx443083-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx443084-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx443363-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx443364-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx443644-100ug 100 ug
EUR 777.6

Dityrosine Antibody

abx443645-100ug 100 ug
EUR 777.6

Dityrosine Antibody

abx443925-100ug 100 ug
EUR 811.2

Dityrosine Antibody

abx443926-100ug 100 ug
EUR 811.2

Dityrosine Antibody

abx442241-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx442242-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx442522-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx442523-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx442803-100ug 100 ug
EUR 794.4

Dityrosine Antibody

abx442804-100ug 100 ug
EUR 794.4

Ditolylguanidine

HY-14218 10mM/1mL
EUR 135.6

Lapatinib Ditosylate

A3967-100 100 mg
EUR 157.2
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib Ditosylate

A3967-5.1 10 mM (in 1mL DMSO)
EUR 205.2
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib Ditosylate

A3967-50 50 mg
EUR 129.6
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib Ditosylate

A3967-S Evaluation Sample
EUR 97.2
Description: Lapatinib Ditosylate is a selective dual inhibitor of ErbB-2 and EGFR with IC50 value against ErbB-2 and EGFR of 9.2 and 10.8 nM in vitro, respectively.

Lapatinib (ditosylate)

HY-50898A 500mg
EUR 274.8

Ditryptophenaline

TBP04426 5mg
EUR 2034

2,7-Di-tert-butylpyrene

20-abx186731
  • EUR 1245.60
  • EUR 543.60
  • 25 g
  • 5 g

Vinorelbine ditartrate

A3921-10 10 mg
EUR 177.6
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine ditartrate

A3921-25 25 mg
EUR 282
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine ditartrate

A3921-5.1 10 mM (in 1mL DMSO)
EUR 324
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine ditartrate

A3921-50 50 mg
EUR 448.8
Description: Description: IC50 Value: 1.25 nM (Hela cell) [1] Vinorelbine is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Vinorelbine (ditartrate)

HY-12053A 10mg
EUR 159.6

Vinorelbine ditartrate

GP5205-10MG 10 mg
EUR 112.8

Vinorelbine ditartrate

GP5205-25MG 25 mg
EUR 170.4

Vinorelbine ditartrate

GP5205-50MG 50 mg
EUR 274.8

Vinorelbine ditartrate

GP5205-5MG 5 mg
EUR 86.4

N,N''-Di-tert-butylthiourea

GW6661-10 10
EUR 214.1

N,N''-Di-tert-butylthiourea

GW6661-50 50
EUR 737

Vinorelbine ditartrate

GP5205-10 10
EUR 63.3

Vinorelbine ditartrate

GP5205-25 25
EUR 110.7

Vinorelbine ditartrate

GP5205-5 5
EUR 41.9

Vinorelbine ditartrate

GP5205-50 50
EUR 197.7

3,5-Di-Tert-Butylcatechol

abx188340-1kg 1 kg
EUR 1980

Di-tert-butyl dicarbonate

GE4403-100G 100 g
EUR 98.4

Di-tert-butyl dicarbonate

GE4403-250G 250 g
EUR 160.8

Di-tert-butyl dicarbonate

GE4403-25G 25 g
EUR 60

Di-tert-butyl dicarbonate

GE4403-500G 500 g
EUR 254.4

Di-tert-butyl dicarbonate

GE4403-100 100
EUR 51.4

Di-tert-butyl dicarbonate

GE4403-25 25
EUR 20.2

Di-tert-butyl dicarbonate

GE4403-250 250
EUR 102.7

Di-tert-butyl dicarbonate

GE4403-500 500
EUR 180

AZ505 ditrifluoroacetate

B1256-10 10 mg
EUR 648
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate

B1256-100 100 mg
EUR 2815.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate

B1256-25 25 mg
EUR 1309.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate

B1256-5 5 mg
EUR 409.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ505 ditrifluoroacetate

B1256-50 50 mg
EUR 1879.2
Description: AZ505 is a potent SET and MYND domain-containing 2 protein (SMYD2) inhibitor that selectively inhibits the enzymatic activity of SMYD2 (IC50: 0.12 ?M) over a variety of other protein lysine methyltransferases (IC50 > 83.3 ??), including SMYD3, DOT1L, EZH2, GLP, G9A and SET7/9 [1].

AZ-505 ditrifluoroacetate

B1883-1 each
EUR 183.6

AZ-505 ditrifluoroacetate

B1883-5 each
EUR 548.4

AZ505 (ditrifluoroacetate)

HY-15226A 50mg
EUR 1695.6

DiTO™-3 [equivalent to TOTO®-3] *5 mM DMSO Solution*

17576 0.2 ml
EUR 222