Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Long intergenic non-protein coding RNA, p53 induced transcript (Linc-pint) is an extended noncoding RNA (lncRNA) that regulates tumor cell viability and proliferation. We used qRT-PCR and RNA FISH evaluation to judge Linc-pint levels within the plasma and tumor tissues of pancreatic most cancers (PCa) sufferers.

Our knowledge exhibit that Linc-pint expression is decrease in plasma samples from PCa sufferers than from wholesome people, and point out that plasma Linc-pint levels are extra delicate than CA19-9 for detecting PCa. Our knowledge additionally present that Linc-pint levels are decrease in PCa tumors than in adjoining tissues, carcinoma of the ampulla of Vater (CAV) and cholangiocarcinoma (CCA), and recommend that Linc-pint may very well be used for distinguishing the trigger of malignant obstructive jaundice.

Low plasma Linc-pint levels correlate with tumor recurrence, whereas low tumor Linc-pint levels correlate with poor prognosis for PCa sufferers after pancreatectomy. These outcomes thus point out that low plasma Linc-pint expression may function a minimally invasive biomarker for early PCa detection, and that low Linc-pint levels in PCa tumors may very well be used for predicting affected person prognosis.

Atypical juvenile neuronal ceroid lipofuscinosis: A report of three circumstances.

The analysis of juvenile neuronal ceroid lipofuscinosis (JNCL) is normally based mostly on age of onset, preliminary scientific signs, scientific development, and pathologic findings. Our circumstances manifested atypical scientific symptomatology and/or pathologic findings and due to this fact, symbolize variant varieties of JNCL. Case 1 and 2 introduced with gradual developmental regression from the age of four years and grew to become blind and wheelchair sure at round eight years.

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.
Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Pathologic discovering of lymphocytes confirmed fingerprint inclusion which was per JNCL. Mutational evaluation was optimistic for CLN5 which normally presents as variant late childish NCL (LINCL) and extra frequent in Finnish inhabitants. Case three introduced with progressive visible loss from the age of eight years. Clinical symptomatology and age of onset have been much like that of JNCL however was discovered to have low palmitoyl protein thioesterase, granular inclusion physique, and CLN1 mutation, thus representing milder kind of INCL. These three circumstances demonstrated phenotypic-genotypic variations. Pertinent points relating diagnostic difficulties, ophthalmologic, neuroradiological, and laboratory facets are mentioned.

H-DL-d-Hydroxy-DL-Lys-OH · HCl

F-1650.0005 5.0g
EUR 385.2
Description: Sum Formula: C6H14N2O3·HCl; CAS# [13204-98-3]

H-DL-Ala-OMe · HCl

F-1150.0025 25.0g
EUR 138
Description: Sum Formula: C4H9NO2·HCl; CAS# [13515-97-4]

H-DL-Ala-OMe · HCl

F-1150.0100 100.0g
EUR 327.6
Description: Sum Formula: C4H9NO2·HCl; CAS# [13515-97-4]

H-DL-Nle-OMe · HCl

F-1935.0025 25.0g
EUR 270
Description: Sum Formula: C7H15NO2·HCl; CAS# [77300-48-2]

H-DL-Nle-OMe · HCl

F-1935.0100 100.0g
EUR 733.2
Description: Sum Formula: C7H15NO2·HCl; CAS# [77300-48-2]

H-DL-Phe-NH2 · HCl

F-1990.0005 5.0g
EUR 138
Description: Sum Formula: C9H12N2O·HCl; CAS# [108321-83-1]

H-DL-Phe-NH2 · HCl

F-1990.0025 25.0g
EUR 441.6
Description: Sum Formula: C9H12N2O·HCl; CAS# [108321-83-1]

H-DL-Phe-OMe · HCl

F-2005.0025 25.0g
EUR 211.2
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Phe-OMe · HCl

F-2005.0250 250.0g
EUR 733.2
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Phe-OMe · HCl

F-2005.1000 1.0kg
EUR 2140.8
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Pro-OMe · HCl

F-2070.0005 5.0g
EUR 211.2
Description: Sum Formula: C6H11NO2·HCl; CAS# [79397-50-5]

H-DL-Pro-OMe · HCl

F-2070.0025 25.0g
EUR 704.4
Description: Sum Formula: C6H11NO2·HCl; CAS# [79397-50-5]

H-DL-Ala-OEt · HCl

F-2095.0025 25.0g
EUR 151.2
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Ala-OEt · HCl

F-2095.0100 100.0g
EUR 400.8
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Ala-OEt · HCl

F-2095.0250 250.0g
EUR 762
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Trp-NH2 · HCl

F-2155.0001 1.0g
EUR 138
Description: Sum Formula: C11H13N3O·HCl; CAS# [67607-61-8]

H-DL-Trp-NH2 · HCl

F-2155.0005 5.0g
EUR 211.2
Description: Sum Formula: C11H13N3O·HCl; CAS# [67607-61-8]

H-DL-Trp-OEt · HCl

F-2160.0025 25.0g
EUR 166.8
Description: Sum Formula: C13H16N2O2·HCl; CAS# [6519-67-1]

H-DL-Trp-OEt · HCl

F-2160.0100 100.0g
EUR 428.4
Description: Sum Formula: C13H16N2O2·HCl; CAS# [6519-67-1]

H-DL-Leu-NH2 · HCl

F-2360.0005 5.0g
EUR 138
Description: Sum Formula: C6H14N2O·HCl; CAS# [10466-60-1]

H-DL-Leu-NH2 · HCl

F-2360.0025 25.0g
EUR 340.8
Description: Sum Formula: C6H14N2O·HCl; CAS# [10466-60-1]

H-DL-Pro-NH2 · HCl

F-2385.0001 1.0g
EUR 138
Description: Sum Formula: C5H10N2O·HCl; CAS# [115630-49-4]

H-DL-Pro-NH2 · HCl

F-2385.0005 5.0g
EUR 313.2
Description: Sum Formula: C5H10N2O·HCl; CAS# [115630-49-4]

H-DL-Met-OMe · HCl

F-2535.0025 25.0g
EUR 151.2
Description: Sum Formula: C6H13NO2S·HCl; CAS# [16118-36-8]

H-DL-Met-OMe · HCl

F-2535.0100 100.0g
EUR 400.8
Description: Sum Formula: C6H13NO2S·HCl; CAS# [16118-36-8]

H-DL-Ser-OMe · HCl

F-2610.0025 25.0g
EUR 166.8
Description: Sum Formula: C4H9NO3·HCl; CAS# [5619-04-5]

H-DL-Ser-OMe · HCl

F-2610.0100 100.0g
EUR 441.6
Description: Sum Formula: C4H9NO3·HCl; CAS# [5619-04-5]

H-DL-Leu-OMe · HCl

F-2925.0025 25.0g
EUR 138
Description: Sum Formula: C7H15NO2·HCl; CAS# [6322-53-8]

H-DL-Leu-OMe · HCl

F-2925.0100 100.0g
EUR 340.8
Description: Sum Formula: C7H15NO2·HCl; CAS# [6322-53-8]

H-DL-Trp-OMe · HCl

F-3435.0005 5.0g
EUR 138
Description: Sum Formula: C12H14N2O2·HCl; CAS# [5619-09-0]

H-DL-Trp-OMe · HCl

F-3435.0025 25.0g
EUR 370.8
Description: Sum Formula: C12H14N2O2·HCl; CAS# [5619-09-0]

H-DL-Tyr-OMe · HCl

F-3600.0025 25.0g
EUR 138
Description: Sum Formula: C10H13NO3·HCl; CAS# [68697-61-0]

H-DL-Tyr-OMe · HCl

F-3600.0100 100.0g
EUR 441.6
Description: Sum Formula: C10H13NO3·HCl; CAS# [68697-61-0]

H-Dl-Phe-Nh2 Hcl

20-abx186465
  • EUR 276.00
  • EUR 1262.40
  • EUR 444.00
  • 1 g
  • 25 g
  • 5 g

Bz-DL-Arg-pNA · HCl

L-1140.0005 5.0g
EUR 138
Description: Sum Formula: C19H22N6O4·HCl; CAS# [911-77-3]

Bz-DL-Arg-pNA · HCl

L-1140.0025 25.0g
EUR 441.6
Description: Sum Formula: C19H22N6O4·HCl; CAS# [911-77-3]

Bz-DL-Arg-AMC · HCl

I-1075.0050 50.0mg
EUR 138
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

Bz-DL-Arg-AMC · HCl

I-1075.0250 250.0mg
EUR 370.8
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

Bz-DL-Arg-AMC · HCl

I-1075.1000 1.0g
EUR 1039.2
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

H-DL-Ala-bNA · HCl

K-1030.0001 1.0g
EUR 138
Description: Sum Formula: C13H14N2O·HCl; CAS# [74144-49-3]

H-DL-Ala-bNA · HCl

K-1030.0005 5.0g
EUR 356.4
Description: Sum Formula: C13H14N2O·HCl; CAS# [74144-49-3]

Bz-DL-Arg-bNA · HCl

K-1125.0001 1.0g
EUR 138
Description: Sum Formula: C23H25N5O2·HCl; CAS# [913-04-2]

Bz-DL-Arg-bNA · HCl

K-1125.0005 5.0g
EUR 211.2
Description: Sum Formula: C23H25N5O2·HCl; CAS# [913-04-2]

H-DL-Met-bNA · HCl

K-1435.0250 250.0mg
EUR 138
Description: Sum Formula: C15H18N2OS·HCl; CAS# [97405-58-8]

H-DL-Met-bNA · HCl

K-1435.1000 1.0g
EUR 240
Description: Sum Formula: C15H18N2OS·HCl; CAS# [97405-58-8]

H-DL-Asp(OMe)-OMe · HCl

F-1280.0025 25.0g
EUR 166.8
Description: Sum Formula: C6H11NO4·HCl; CAS# [14358-33-9]

H-DL-Asp(OMe)-OMe · HCl

F-1280.0100 100.0g
EUR 428.4
Description: Sum Formula: C6H11NO4·HCl; CAS# [14358-33-9]

H-DL-Asp(OMe)-OH · HCl

F-3240.0001 1.0g
EUR 138
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

H-DL-Asp(OMe)-OH · HCl

F-3240.0005 5.0g
EUR 327.6
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

H-DL-Asp(OMe)-OH · HCl

F-3240.0025 25.0g
EUR 1197.6
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

N-Me-DL-Phe-OMe · HCl

F-3545.0001 1.0g
EUR 327.6
Description: Sum Formula: C11H15NO2·HCl; CAS# [16975-45-4]

N-Me-DL-Phe-OMe · HCl

F-3545.0005 5.0g
EUR 1197.6
Description: Sum Formula: C11H15NO2·HCl; CAS# [16975-45-4]

H-p-Chloro-DL-Phe-OMe · HCl

F-1455.0005 5.0g
EUR 240
Description: Sum Formula: C10H12ClNO2·HCl; CAS# [14173-40-1]

H-p-Chloro-DL-Phe-OMe · HCl

F-1455.0025 25.0g
EUR 819.6
Description: Sum Formula: C10H12ClNO2·HCl; CAS# [14173-40-1]

H-p-Fluoro-DL-Phe-OMe · HCl

F-1540.0001 1.0g
EUR 138
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-p-Fluoro-DL-Phe-OMe · HCl

F-1540.0005 5.0g
EUR 240
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-p-Fluoro-DL-Phe-OMe · HCl

F-1540.0025 25.0g
EUR 835.2
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-b-Chloro-DL-Ala-OH · HCl

F-2325.0001 1.0g
EUR 138
Description: Sum Formula: C3H6ClNO2·HCl; CAS# [35401-46-8]

H-b-Chloro-DL-Ala-OH · HCl

F-2325.0005 5.0g
EUR 370.8
Description: Sum Formula: C3H6ClNO2·HCl; CAS# [35401-46-8]

H-a-Me-DL-Phe-OMe · HCl

F-2805.0005 5.0g
EUR 327.6
Description: Sum Formula: C11H15NO2·HCl; CAS# [64665-60-7]

H-a-Me-DL-Phe-OMe · HCl

F-2805.0025 25.0g
EUR 1197.6
Description: Sum Formula: C11H15NO2·HCl; CAS# [64665-60-7]

H-a-Me-DL-His-OH · 2 HCl

F-1795.0250 250.0mg
EUR 211.2
Description: Sum Formula: C7H11N3O2·2HCl; CAS# [32381-18-3]

H-a-Me-DL-His-OH · 2 HCl

F-1795.1000 1.0g
EUR 559.2
Description: Sum Formula: C7H11N3O2·2HCl; CAS# [32381-18-3]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O

F-2395.0050 50.0mg
EUR 138
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O

F-2395.0250 250.0mg
EUR 327.6
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O

F-2395.1000 1.0g
EUR 907.2
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-trans-4,5-Dehydro-DL-Lys-OH · 2 HCl

F-2970.0250 250.0mg
EUR 370.8
Description: Sum Formula: C6H12N2O2·2HCl; CAS# [39871-25-5] net

H-trans-4,5-Dehydro-DL-Lys-OH · 2 HCl

F-2970.1000 1.0g
EUR 1039.2
Description: Sum Formula: C6H12N2O2·2HCl; CAS# [39871-25-5] net

H-DL-Ala-DL-Ala-OH

G-1140.0005 5.0g
EUR 211.2
Description: Sum Formula: C6H12N2O3; CAS# [2867-20-1]

H-DL-Ala-DL-Ala-OH

G-1140.0025 25.0g
EUR 733.2
Description: Sum Formula: C6H12N2O3; CAS# [2867-20-1]

H-DL-Leu-DL-Ala-OH

G-2470.0005 5.0g
EUR 151.2
Description: Sum Formula: C9H18N2O3; CAS# [5060-46-8]

H-DL-Leu-DL-Ala-OH

G-2470.0025 25.0g
EUR 501.6
Description: Sum Formula: C9H18N2O3; CAS# [5060-46-8]

DL-Cycloserine

F-1485.0050 50.0mg
EUR 254.4
Description: Sum Formula: C3H6N2O2; CAS# [68-39-3]

DL-Cycloserine

F-1485.0250 250.0mg
EUR 907.2
Description: Sum Formula: C3H6N2O2; CAS# [68-39-3]

DL-Cycloserine

F-1485.1000 1.0g
EUR 2648.4
Description: Sum Formula: C3H6N2O2; CAS# [68-39-3]

DL-Thyronine

F-2405.0001 1.0g
EUR 254.4
Description: Sum Formula: C15H15NO4; CAS# [1034-10-2]

DL-Thyronine

F-2405.0005 5.0g
EUR 907.2
Description: Sum Formula: C15H15NO4; CAS# [1034-10-2]

DL-Penylalaninol

5-07735 5g Ask for price

DL-Penylalaninol

5-07736 25g Ask for price

DL-Phenylglycinol

5-07747 25g Ask for price

DL-Phenylglycinol

5-07748 100g Ask for price

DL-Prolinol

5-07763 5g Ask for price

DL-Prolinol

5-07764 25g Ask for price

DL-AP3

A4535-100 100 mg
EUR 236.4
Description: Competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.

DL-Naproxen

20-abx182435
  • EUR 427.20
  • EUR 292.80
  • EUR 243.60
  • 100 g
  • 25 g
  • 5 g

DL-Cystine

20-abx184678
  • EUR 661.20
  • EUR 360.00
  • EUR 243.60
  • 100 g
  • 25 g
  • 5 g

DL-Isoleucine

20-abx184679
  • EUR 410.40
  • EUR 276.00
  • EUR 226.80
  • 100 g
  • 25 g
  • 5 g

DL-Panthenol

20-abx184680
  • EUR 343.20
  • EUR 260.40
  • EUR 610.80
  • 100 g
  • 25 g
  • 500 g

DL-Valine

20-abx185402
  • EUR 594.00
  • EUR 444.00
  • 1 kg
  • 500 g

DL-Lysine

20-abx185976
  • EUR 343.20
  • EUR 243.60
  • 100 g
  • 10 g

DL-Dopa

abx187922-1000g 1000 g
EUR 861.6

DL-TBOA

B5084-10 10 mg
EUR 466.8
Description: Ki: 42 ?M for EAAT1; 5.7 ?M for EAAT2Glutamate acts as an excitatory neurotransmitter in the mammalian central nervous system and a potent neurotoxin.

DL-TBOA

B5084-50 50 mg
EUR 1771.2
Description: Ki: 42 ?M for EAAT1; 5.7 ?M for EAAT2Glutamate acts as an excitatory neurotransmitter in the mammalian central nervous system and a potent neurotoxin.

DL-Adrenaline

B1326-50 50 mg
EUR 153.6
Description: DL-Epinephrine(DL-Adrenaline) is a hormone and a neurotransmitter.

DL-AP4

B6200-100 100 mg
EUR 243.6

DL-AP7

B6203-10 10 mg
EUR 290.4

DL-AP7

B6203-50 50 mg
EUR 973.2

DL-AP5

B6204-10 10 mg
EUR 158.4

DL-AP5

B6204-25 25 mg
EUR 290.4

DL-AP5

B6204-50 50 mg
EUR 493.2

DL-Aminoglutethimide

B2040-100
EUR 144

DL-Aminoglutethimide

B2040-500
EUR 314.4

DL-Dithiothreitol

B7294-25000 25 g
EUR 358.8

DL-Phosphinothricin

P034-1G 1 g
EUR 324

DL-Phosphinothricin

P034-250MG 250 mg
EUR 92.4

DL-Thiorphan

N-1195.0025 25.0mg
EUR 400.8
Description: Sum Formula: C12H15NO3S; CAS# [76721-89-6]

DL-Thiorphan

N-1195.0100 100.0mg
EUR 1125.6
Description: Sum Formula: C12H15NO3S; CAS# [76721-89-6]

DL-Menthol

N1875-20 20 mg
EUR 115.2
Description: Extracted from Herba Menthae Haplocalycis;Suitability:Alcohol,ether,acetic acid,liquid paraffin and petroleum ether;Store the product in sealed,cool and dry condition

DL-Homocystine

HY-W009390 5g
EUR 142.8

DL-Norvaline

HY-W010510 5g
EUR 142.8

DL-Homocysteine

HY-W040821 10mM/1mL
EUR 151.2

DL-Serine

HY-Y0507 100mg
EUR 129.6

DL-Menthol

HY-Y1683 100mg
EUR 129.6

DL-Menthol

GL0768-100G 100 g
EUR 72

DL-Menthol

GL0768-250G 250 g
EUR 99.6

DL-Thiorphan

GL2922-25MG 25 mg
EUR 303.6

DL-Thiorphan

GL2922-5MG 5 mg
EUR 122.4

DL-Tryptophan

GM0325-100G 100 g
EUR 208.8

DL-Tryptophan

GM0325-25G 25 g
EUR 93.6

DL-Tryptophan

GM0325-5G 5 g
EUR 55.2

DL-Homoserine

GM0565-1G 1 g
EUR 74.4

DL-Homoserine

GM0565-5G 5 g
EUR 147.6

DL-Isoleucine

GM0912-100G 100 g
EUR 208.8

DL-Isoleucine

GM0912-10G 10 g
EUR 60

DL-Isoleucine

GM0912-25G 25 g
EUR 93.6

DL-Isoleucine

GM0912-50G 50 g
EUR 132

DL-Isoleucine

GM0912-5G 5 g
EUR 55.2

DL-Norleucine

GM0955-100G 100 g
EUR 180

DL-Norleucine

GM0955-25G 25 g
EUR 84

DL-Methionine

GM2607-100G 100 g
EUR 52.8

DL-Methionine

GM2607-1KG 1 kg
EUR 112.8

DL-Methionine

GM2607-250G 250 g
EUR 63.6

DL-Methionine

GM2607-500G 500 g
EUR 79.2

DL-Methionine

GM2607-5KG 5 kg
EUR 274.8

DL-Valine

GM3274-100G 100 g
EUR 79.2

DL-Valine

GM3274-1KG 1 kg
EUR 313.2

DL-Valine

GM3274-250G 250 g
EUR 122.4

DL-Valine

GM3274-25G 25 g
EUR 55.2

DL-Valine

GM3274-500G 500 g
EUR 189.6

DL-Alanine

GM4363-100G 100 g
EUR 55.2

DL-Alanine

GM4363-1KG 1 kg
EUR 122.4

DL-Alanine

GM4363-250G 250 g
EUR 63.6

DL-Alanine

GM4363-25G 25 g
EUR 48

DL-Alanine

GM4363-500G 500 g
EUR 84

DL-Alanine

GM4363-5KG 5 kg
EUR 337.2

DL-Cystine

GM5088-1G 1 g
EUR 74.4

DL-Cystine

GM5088-5G 5 g
EUR 151.2

DL-Phenylalanine

GM5287-100G 100 g
EUR 93.6

DL-Phenylalanine

GM5287-1KG 1 kg
EUR 313.2

DL-Phenylalanine

GM5287-250G 250 g
EUR 132

DL-Phenylalanine

GM5287-25G 25 g
EUR 60

DL-Phenylalanine

GM5287-500G 500 g
EUR 199.2

DL-Histidine

GM6216-100G 100 g
EUR 294

DL-Histidine

GM6216-25G 25 g
EUR 132

DL-Histidine

GM6216-5G 5 g
EUR 69.6

DL-Cysteine

GM6393-1G 1 g
EUR 64.8

DL-Tyrosine

GM6469-100G 100 g
EUR 180

DL-Tyrosine

GM6469-10G 10 g
EUR 60

DL-Tyrosine

GM6469-250G 250 g
EUR 322.8

DL-Tyrosine

GM6469-25G 25 g
EUR 84

DL-Tyrosine

GM6469-50G 50 g
EUR 122.4

DL-Proline

GM7043-100G 100 g
EUR 370.8

DL-Proline

GM7043-1G 1 g
EUR 55.2

DL-Proline

GM7043-25G 25 g
EUR 170.4

DL-Proline

GM7043-5G 5 g
EUR 79.2

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