Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Leave a Comment / Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer. / By

Long intergenic non-protein coding RNA, p53 induced transcript (Linc-pint) is an extended noncoding RNA (lncRNA) that regulates tumor cell viability and proliferation. We used qRT-PCR and RNA FISH evaluation to judge Linc-pint levels within the plasma and tumor tissues of pancreatic most cancers (PCa) sufferers.

Our knowledge exhibit that Linc-pint expression is decrease in plasma samples from PCa sufferers than from wholesome people, and point out that plasma Linc-pint levels are extra delicate than CA19-9 for detecting PCa. Our knowledge additionally present that Linc-pint levels are decrease in PCa tumors than in adjoining tissues, carcinoma of the ampulla of Vater (CAV) and cholangiocarcinoma (CCA), and recommend that Linc-pint may very well be used for distinguishing the trigger of malignant obstructive jaundice.

Low plasma Linc-pint levels correlate with tumor recurrence, whereas low tumor Linc-pint levels correlate with poor prognosis for PCa sufferers after pancreatectomy. These outcomes thus point out that low plasma Linc-pint expression may function a minimally invasive biomarker for early PCa detection, and that low Linc-pint levels in PCa tumors may very well be used for predicting affected person prognosis.

Atypical juvenile neuronal ceroid lipofuscinosis: A report of three circumstances.

The analysis of juvenile neuronal ceroid lipofuscinosis (JNCL) is normally based mostly on age of onset, preliminary scientific signs, scientific development, and pathologic findings. Our circumstances manifested atypical scientific symptomatology and/or pathologic findings and due to this fact, symbolize variant varieties of JNCL. Case 1 and 2 introduced with gradual developmental regression from the age of four years and grew to become blind and wheelchair sure at round eight years.

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.
Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Pathologic discovering of lymphocytes confirmed fingerprint inclusion which was per JNCL. Mutational evaluation was optimistic for CLN5 which normally presents as variant late childish NCL (LINCL) and extra frequent in Finnish inhabitants. Case three introduced with progressive visible loss from the age of eight years. Clinical symptomatology and age of onset have been much like that of JNCL however was discovered to have low palmitoyl protein thioesterase, granular inclusion physique, and CLN1 mutation, thus representing milder kind of INCL. These three circumstances demonstrated phenotypic-genotypic variations. Pertinent points relating diagnostic difficulties, ophthalmologic, neuroradiological, and laboratory facets are mentioned.

DL-Carnitine HCl
B1934-S Evaluation Sample
EUR 81
Description: DL-Carnitine HCl

H-DL-d-Hydroxy-DL-Lys-OH · HCl
F-1650.0001 1.0g
EUR 115
Description: Sum Formula: C6H14N2O3·HCl; CAS# [13204-98-3]

H-DL-d-Hydroxy-DL-Lys-OH · HCl
F-1650.0005 5.0g
EUR 321
Description: Sum Formula: C6H14N2O3·HCl; CAS# [13204-98-3]

H-DL-Nle-OMe · HCl
F-1935.0025 25.0g
EUR 225
Description: Sum Formula: C7H15NO2·HCl; CAS# [77300-48-2]

H-DL-Nle-OMe · HCl
F-1935.0100 100.0g
EUR 611
Description: Sum Formula: C7H15NO2·HCl; CAS# [77300-48-2]

H-DL-Phe-NH2 · HCl
F-1990.0005 5.0g
EUR 115
Description: Sum Formula: C9H12N2O·HCl; CAS# [108321-83-1]

H-DL-Phe-NH2 · HCl
F-1990.0025 25.0g
EUR 368
Description: Sum Formula: C9H12N2O·HCl; CAS# [108321-83-1]

H-DL-Phe-OMe · HCl
F-2005.0025 25.0g
EUR 176
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Phe-OMe · HCl
F-2005.0250 250.0g
EUR 611
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Phe-OMe · HCl
F-2005.1000 1.0kg
EUR 1784
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Pro-OMe · HCl
F-2070.0005 5.0g
EUR 176
Description: Sum Formula: C6H11NO2·HCl; CAS# [79397-50-5]

H-DL-Pro-OMe · HCl
F-2070.0025 25.0g
EUR 587
Description: Sum Formula: C6H11NO2·HCl; CAS# [79397-50-5]

H-DL-Ala-OEt · HCl
F-2095.0025 25.0g
EUR 126
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Ala-OEt · HCl
F-2095.0100 100.0g
EUR 334
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Ala-OEt · HCl
F-2095.0250 250.0g
EUR 635
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Trp-NH2 · HCl
F-2155.0001 1.0g
EUR 115
Description: Sum Formula: C11H13N3O·HCl; CAS# [67607-61-8]

H-DL-Trp-NH2 · HCl
F-2155.0005 5.0g
EUR 176
Description: Sum Formula: C11H13N3O·HCl; CAS# [67607-61-8]

H-DL-Trp-OEt · HCl
F-2160.0025 25.0g
EUR 139
Description: Sum Formula: C13H16N2O2·HCl; CAS# [6519-67-1]

H-DL-Trp-OEt · HCl
F-2160.0100 100.0g
EUR 357
Description: Sum Formula: C13H16N2O2·HCl; CAS# [6519-67-1]

H-DL-Leu-NH2 · HCl
F-2360.0005 5.0g
EUR 115
Description: Sum Formula: C6H14N2O·HCl; CAS# [10466-60-1]

H-DL-Leu-NH2 · HCl
F-2360.0025 25.0g
EUR 284
Description: Sum Formula: C6H14N2O·HCl; CAS# [10466-60-1]

H-DL-Pro-NH2 · HCl
F-2385.0001 1.0g
EUR 115
Description: Sum Formula: C5H10N2O·HCl; CAS# [115630-49-4]

H-DL-Pro-NH2 · HCl
F-2385.0005 5.0g
EUR 261
Description: Sum Formula: C5H10N2O·HCl; CAS# [115630-49-4]

H-DL-Met-OMe · HCl
F-2535.0025 25.0g
EUR 126
Description: Sum Formula: C6H13NO2S·HCl; CAS# [16118-36-8]

H-DL-Met-OMe · HCl
F-2535.0100 100.0g
EUR 334
Description: Sum Formula: C6H13NO2S·HCl; CAS# [16118-36-8]

H-DL-Ser-OMe · HCl
F-2610.0025 25.0g
EUR 139
Description: Sum Formula: C4H9NO3·HCl; CAS# [5619-04-5]

H-DL-Ser-OMe · HCl
F-2610.0100 100.0g
EUR 368
Description: Sum Formula: C4H9NO3·HCl; CAS# [5619-04-5]

H-DL-Leu-OMe · HCl
F-2925.0025 25.0g
EUR 115
Description: Sum Formula: C7H15NO2·HCl; CAS# [6322-53-8]

H-DL-Leu-OMe · HCl
F-2925.0100 100.0g
EUR 284
Description: Sum Formula: C7H15NO2·HCl; CAS# [6322-53-8]

H-DL-Trp-OMe · HCl
F-3435.0005 5.0g
EUR 115
Description: Sum Formula: C12H14N2O2·HCl; CAS# [5619-09-0]

H-DL-Trp-OMe · HCl
F-3435.0025 25.0g
EUR 309
Description: Sum Formula: C12H14N2O2·HCl; CAS# [5619-09-0]

H-DL-Tyr-OMe · HCl
F-3600.0025 25.0g
EUR 115
Description: Sum Formula: C10H13NO3·HCl; CAS# [68697-61-0]

H-DL-Tyr-OMe · HCl
F-3600.0100 100.0g
EUR 368
Description: Sum Formula: C10H13NO3·HCl; CAS# [68697-61-0]

H-DL-Ala-OMe · HCl
F-1150.0025 25.0g
EUR 115
Description: Sum Formula: C4H9NO2·HCl; CAS# [13515-97-4]

H-DL-Ala-OMe · HCl
F-1150.0100 100.0g
EUR 273
Description: Sum Formula: C4H9NO2·HCl; CAS# [13515-97-4]

H-DL-Ala-bNA · HCl
K-1030.0001 1.0g
EUR 115
Description: Sum Formula: C13H14N2O·HCl; CAS# [74144-49-3]

H-DL-Ala-bNA · HCl
K-1030.0005 5.0g
EUR 297
Description: Sum Formula: C13H14N2O·HCl; CAS# [74144-49-3]

Bz-DL-Arg-bNA · HCl
K-1125.0001 1.0g
EUR 115
Description: Sum Formula: C23H25N5O2·HCl; CAS# [913-04-2]

Bz-DL-Arg-bNA · HCl
K-1125.0005 5.0g
EUR 176
Description: Sum Formula: C23H25N5O2·HCl; CAS# [913-04-2]

H-DL-Met-bNA · HCl
K-1435.0250 250.0mg
EUR 115
Description: Sum Formula: C15H18N2OS·HCl; CAS# [97405-58-8]

H-DL-Met-bNA · HCl
K-1435.1000 1.0g
EUR 200
Description: Sum Formula: C15H18N2OS·HCl; CAS# [97405-58-8]

Bz-DL-Arg-AMC · HCl
I-1075.0050 50.0mg
EUR 115
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

Bz-DL-Arg-AMC · HCl
I-1075.0250 250.0mg
EUR 309
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

Bz-DL-Arg-AMC · HCl
I-1075.1000 1.0g
EUR 866
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

H-Dl-Phe-Nh2 Hcl
20-abx186465
  • EUR 230.00
  • EUR 1052.00
  • EUR 370.00
  • 1 g
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

Bz-DL-Arg-pNA · HCl
L-1140.0005 5.0g
EUR 115
Description: Sum Formula: C19H22N6O4·HCl; CAS# [911-77-3]

Bz-DL-Arg-pNA · HCl
L-1140.0025 25.0g
EUR 368
Description: Sum Formula: C19H22N6O4·HCl; CAS# [911-77-3]

H-DL-Asp(OMe)-OH · HCl
F-3240.0001 1.0g
EUR 115
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

H-DL-Asp(OMe)-OH · HCl
F-3240.0005 5.0g
EUR 273
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

H-DL-Asp(OMe)-OH · HCl
F-3240.0025 25.0g
EUR 998
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

N-Me-DL-Phe-OMe · HCl
F-3545.0001 1.0g
EUR 273
Description: Sum Formula: C11H15NO2·HCl; CAS# [16975-45-4]

N-Me-DL-Phe-OMe · HCl
F-3545.0005 5.0g
EUR 998
Description: Sum Formula: C11H15NO2·HCl; CAS# [16975-45-4]

H-DL-Asp(OMe)-OMe · HCl
F-1280.0025 25.0g
EUR 139
Description: Sum Formula: C6H11NO4·HCl; CAS# [14358-33-9]

H-DL-Asp(OMe)-OMe · HCl
F-1280.0100 100.0g
EUR 357
Description: Sum Formula: C6H11NO4·HCl; CAS# [14358-33-9]

H-b-Chloro-DL-Ala-OH · HCl
F-2325.0001 1.0g
EUR 115
Description: Sum Formula: C3H6ClNO2·HCl; CAS# [35401-46-8]

H-b-Chloro-DL-Ala-OH · HCl
F-2325.0005 5.0g
EUR 309
Description: Sum Formula: C3H6ClNO2·HCl; CAS# [35401-46-8]

H-a-Me-DL-Phe-OMe · HCl
F-2805.0005 5.0g
EUR 273
Description: Sum Formula: C11H15NO2·HCl; CAS# [64665-60-7]

H-a-Me-DL-Phe-OMe · HCl
F-2805.0025 25.0g
EUR 998
Description: Sum Formula: C11H15NO2·HCl; CAS# [64665-60-7]

H-p-Chloro-DL-Phe-OMe · HCl
F-1455.0005 5.0g
EUR 200
Description: Sum Formula: C10H12ClNO2·HCl; CAS# [14173-40-1]

H-p-Chloro-DL-Phe-OMe · HCl
F-1455.0025 25.0g
EUR 683
Description: Sum Formula: C10H12ClNO2·HCl; CAS# [14173-40-1]

H-p-Fluoro-DL-Phe-OMe · HCl
F-1540.0001 1.0g
EUR 115
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-p-Fluoro-DL-Phe-OMe · HCl
F-1540.0005 5.0g
EUR 200
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-p-Fluoro-DL-Phe-OMe · HCl
F-1540.0025 25.0g
EUR 696
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-a-Me-DL-His-OH · 2 HCl
F-1795.0250 250.0mg
EUR 176
Description: Sum Formula: C7H11N3O2·2HCl; CAS# [32381-18-3]

H-a-Me-DL-His-OH · 2 HCl
F-1795.1000 1.0g
EUR 466
Description: Sum Formula: C7H11N3O2·2HCl; CAS# [32381-18-3]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O
F-2395.0050 50.0mg
EUR 115
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O
F-2395.0250 250.0mg
EUR 273
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O
F-2395.1000 1.0g
EUR 756
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-trans-4,5-Dehydro-DL-Lys-OH · 2 HCl
F-2970.0250 250.0mg
EUR 309
Description: Sum Formula: C6H12N2O2·2HCl; CAS# [39871-25-5] net

H-trans-4,5-Dehydro-DL-Lys-OH · 2 HCl
F-2970.1000 1.0g
EUR 866
Description: Sum Formula: C6H12N2O2·2HCl; CAS# [39871-25-5] net

H-DL-Ala-DL-Ala-OH
G-1140.0005 5.0g
EUR 176
Description: Sum Formula: C6H12N2O3; CAS# [2867-20-1]

H-DL-Ala-DL-Ala-OH
G-1140.0025 25.0g
EUR 611
Description: Sum Formula: C6H12N2O3; CAS# [2867-20-1]

H-DL-Leu-DL-Ala-OH
G-2470.0005 5.0g
EUR 126
Description: Sum Formula: C9H18N2O3; CAS# [5060-46-8]

H-DL-Leu-DL-Ala-OH
G-2470.0025 25.0g
EUR 418
Description: Sum Formula: C9H18N2O3; CAS# [5060-46-8]

DL-Aminoglutethimide
B2040-100
EUR 120

DL-Aminoglutethimide
B2040-500
EUR 262

DL-AP4
B6200-100 100 mg
EUR 203

DL-AP7
B6203-10 10 mg
EUR 242

DL-AP7
B6203-50 50 mg
EUR 811

DL-AP5
B6204-10 10 mg
EUR 132

DL-AP5
B6204-25 25 mg
EUR 242

DL-AP5
B6204-50 50 mg
EUR 411

DL-Adrenaline
B1326-50 50 mg
EUR 128
Description: DL-Epinephrine(DL-Adrenaline) is a hormone and a neurotransmitter.

DL-TBOA
B5084-10 10 mg
EUR 389
Description: Ki: 42 ?M for EAAT1; 5.7 ?M for EAAT2Glutamate acts as an excitatory neurotransmitter in the mammalian central nervous system and a potent neurotoxin.

DL-TBOA
B5084-50 50 mg
EUR 1476
Description: Ki: 42 ?M for EAAT1; 5.7 ?M for EAAT2Glutamate acts as an excitatory neurotransmitter in the mammalian central nervous system and a potent neurotoxin.

DL-Dithiothreitol
B7294-25000 25 g
EUR 299

DL-TBOA
HY-107522 10mM/1mL
EUR 563

DL-Carnitine
HY-B0399A 500mg
EUR 108

DL-Epinephrine
HY-B0447 500mg
EUR 108

DL-Panthenol
HY-B1024 10mM/1mL
EUR 113

DL-Xylose
HY-B1070 100mg
EUR 119

DL-Glutamine
HY-B1346 100mg
EUR 119

DL-Lysine
HY-B2236 1g
EUR 119

DL-Dopa
HY-113404 10mM/1mL
EUR 113

DL-Pantolactone
GX6080-10G 10 g
EUR 50

DL-Pantolactone
GX6080-25G 25 g
EUR 61

DL-Menthol
GL0768-100G 100 g
EUR 60

DL-Menthol
GL0768-250G 250 g
EUR 83

DL-Thiorphan
GL2922-25MG 25 mg
EUR 253

DL-Thiorphan
GL2922-5MG 5 mg
EUR 102

DL-Tryptophan
GM0325-100G 100 g
EUR 174

DL-Tryptophan
GM0325-25G 25 g
EUR 78

DL-Tryptophan
GM0325-5G 5 g
EUR 46

DL-Homoserine
GM0565-1G 1 g
EUR 62

DL-Homoserine
GM0565-5G 5 g
EUR 123

DL-Isoleucine
GM0912-100G 100 g
EUR 174

DL-Isoleucine
GM0912-10G 10 g
EUR 50

DL-Isoleucine
GM0912-25G 25 g
EUR 78

DL-Isoleucine
GM0912-50G 50 g
EUR 110

DL-Isoleucine
GM0912-5G 5 g
EUR 46

DL-Norleucine
GM0955-100G 100 g
EUR 150

DL-Norleucine
GM0955-25G 25 g
EUR 70

DL-Methionine
GM2607-100G 100 g
EUR 44

DL-Methionine
GM2607-1KG 1 kg
EUR 94

DL-Methionine
GM2607-250G 250 g
EUR 53

DL-Methionine
GM2607-500G 500 g
EUR 66

DL-Methionine
GM2607-5KG 5 kg
EUR 229

DL-Valine
GM3274-100G 100 g
EUR 66

DL-Valine
GM3274-1KG 1 kg
EUR 261

DL-Valine
GM3274-250G 250 g
EUR 102

DL-Valine
GM3274-25G 25 g
EUR 46

DL-Valine
GM3274-500G 500 g
EUR 158

DL-Alanine
GM4363-100G 100 g
EUR 46

DL-Alanine
GM4363-1KG 1 kg
EUR 102

DL-Alanine
GM4363-250G 250 g
EUR 53

DL-Alanine
GM4363-25G 25 g
EUR 40

DL-Alanine
GM4363-500G 500 g
EUR 70

DL-Alanine
GM4363-5KG 5 kg
EUR 281

DL-Cystine
GM5088-1G 1 g
EUR 62

DL-Cystine
GM5088-5G 5 g
EUR 126

DL-Phenylalanine
GM5287-100G 100 g
EUR 78

DL-Phenylalanine
GM5287-1KG 1 kg
EUR 261

DL-Phenylalanine
GM5287-250G 250 g
EUR 110

DL-Phenylalanine
GM5287-25G 25 g
EUR 50

DL-Phenylalanine
GM5287-500G 500 g
EUR 166

DL-Histidine
GM6216-100G 100 g
EUR 245

DL-Histidine
GM6216-25G 25 g
EUR 110

DL-Histidine
GM6216-5G 5 g
EUR 58

DL-Cysteine
GM6393-1G 1 g
EUR 54

DL-Tyrosine
GM6469-100G 100 g
EUR 150

DL-Tyrosine
GM6469-10G 10 g
EUR 50

DL-Tyrosine
GM6469-250G 250 g
EUR 269

DL-Tyrosine
GM6469-25G 25 g
EUR 70

DL-Tyrosine
GM6469-50G 50 g
EUR 102

DL-Proline
GM7043-100G 100 g
EUR 309

DL-Proline
GM7043-1G 1 g
EUR 46

DL-Proline
GM7043-25G 25 g
EUR 142

DL-Proline
GM7043-5G 5 g
EUR 66

DL-Arginine
GM7749-25G 25 g
EUR 102

DL-Arginine
GM7749-5G 5 g
EUR 50

DL-Threonine
GM8351-100G 100 g
EUR 102

DL-Threonine
GM8351-250G 250 g
EUR 181

DL-Threonine
GM8351-25G 25 g
EUR 54

DL-Threonine
GM8351-500G 500 g
EUR 309

DL-Serine
GM9506-100G 100 g
EUR 62

DL-Serine
GM9506-1KG 1 kg
EUR 269

DL-Serine
GM9506-250G 250 g
EUR 106

DL-Serine
GM9506-500G 500 g
EUR 174

DL-Leucine
GM9742-100G 100 g
EUR 94

DL-Leucine
GM9742-250G 250 g
EUR 181

DL-Leucine
GM9742-25G 25 g
EUR 54

DL-Leucine
GM9742-50G 50 g
EUR 72

DL-Lysine
GM9803-1G 1 g
EUR 42

DL-Lysine
GM9803-5G 5 g
EUR 62

DL-Thyronine
F-2405.0001 1.0g
EUR 212
Description: Sum Formula: C15H15NO4; CAS# [1034-10-2]

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