Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Long intergenic non-protein coding RNA, p53 induced transcript (Linc-pint) is an extended noncoding RNA (lncRNA) that regulates tumor cell viability and proliferation. We used qRT-PCR and RNA FISH evaluation to judge Linc-pint levels within the plasma and tumor tissues of pancreatic most cancers (PCa) sufferers.

Our knowledge exhibit that Linc-pint expression is decrease in plasma samples from PCa sufferers than from wholesome people, and point out that plasma Linc-pint levels are extra delicate than CA19-9 for detecting PCa. Our knowledge additionally present that Linc-pint levels are decrease in PCa tumors than in adjoining tissues, carcinoma of the ampulla of Vater (CAV) and cholangiocarcinoma (CCA), and recommend that Linc-pint may very well be used for distinguishing the trigger of malignant obstructive jaundice.

Low plasma Linc-pint levels correlate with tumor recurrence, whereas low tumor Linc-pint levels correlate with poor prognosis for PCa sufferers after pancreatectomy. These outcomes thus point out that low plasma Linc-pint expression may function a minimally invasive biomarker for early PCa detection, and that low Linc-pint levels in PCa tumors may very well be used for predicting affected person prognosis.

Atypical juvenile neuronal ceroid lipofuscinosis: A report of three circumstances.

The analysis of juvenile neuronal ceroid lipofuscinosis (JNCL) is normally based mostly on age of onset, preliminary scientific signs, scientific development, and pathologic findings. Our circumstances manifested atypical scientific symptomatology and/or pathologic findings and due to this fact, symbolize variant varieties of JNCL. Case 1 and 2 introduced with gradual developmental regression from the age of four years and grew to become blind and wheelchair sure at round eight years.

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.
Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer.

Pathologic discovering of lymphocytes confirmed fingerprint inclusion which was per JNCL. Mutational evaluation was optimistic for CLN5 which normally presents as variant late childish NCL (LINCL) and extra frequent in Finnish inhabitants. Case three introduced with progressive visible loss from the age of eight years. Clinical symptomatology and age of onset have been much like that of JNCL however was discovered to have low palmitoyl protein thioesterase, granular inclusion physique, and CLN1 mutation, thus representing milder kind of INCL. These three circumstances demonstrated phenotypic-genotypic variations. Pertinent points relating diagnostic difficulties, ophthalmologic, neuroradiological, and laboratory facets are mentioned.

DL-Carnitine HCl

B1934-S Evaluation Sample
EUR 81.00
Description: DL-Carnitine HCl

H-DL-d-Hydroxy-DL-Lys-OH · HCl

F-1650.0001 1.0g
EUR 115.00
Description: Sum Formula: C6H14N2O3·HCl; CAS# [13204-98-3]

H-DL-d-Hydroxy-DL-Lys-OH · HCl

F-1650.0005 5.0g
EUR 321.00
Description: Sum Formula: C6H14N2O3·HCl; CAS# [13204-98-3]

H-Dl-Phe-Nh2 Hcl

20-abx186465
  • EUR 230.00
  • EUR 1052.00
  • EUR 370.00
  • 0
  • 1
  • 2
  • Shipped within 1-2 weeks.

H-DL-Ala-OMe · HCl

F-1150.0025 25.0g
EUR 115.00
Description: Sum Formula: C4H9NO2·HCl; CAS# [13515-97-4]

H-DL-Ala-OMe · HCl

F-1150.0100 100.0g
EUR 273.00
Description: Sum Formula: C4H9NO2·HCl; CAS# [13515-97-4]

H-DL-Nle-OMe · HCl

F-1935.0025 25.0g
EUR 225.00
Description: Sum Formula: C7H15NO2·HCl; CAS# [77300-48-2]

H-DL-Nle-OMe · HCl

F-1935.0100 100.0g
EUR 611.00
Description: Sum Formula: C7H15NO2·HCl; CAS# [77300-48-2]

H-DL-Phe-NH2 · HCl

F-1990.0005 5.0g
EUR 115.00
Description: Sum Formula: C9H12N2O·HCl; CAS# [108321-83-1]

H-DL-Phe-NH2 · HCl

F-1990.0025 25.0g
EUR 368.00
Description: Sum Formula: C9H12N2O·HCl; CAS# [108321-83-1]

H-DL-Phe-OMe · HCl

F-2005.0025 25.0g
EUR 176.00
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Phe-OMe · HCl

F-2005.0250 250.0g
EUR 611.00
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Phe-OMe · HCl

F-2005.1000 1.0kg
EUR 1784.00
Description: Sum Formula: C10H13NO2·HCl; CAS# [5619-07-8]

H-DL-Pro-OMe · HCl

F-2070.0005 5.0g
EUR 176.00
Description: Sum Formula: C6H11NO2·HCl; CAS# [79397-50-5]

H-DL-Pro-OMe · HCl

F-2070.0025 25.0g
EUR 587.00
Description: Sum Formula: C6H11NO2·HCl; CAS# [79397-50-5]

H-DL-Ala-OEt · HCl

F-2095.0025 25.0g
EUR 126.00
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Ala-OEt · HCl

F-2095.0100 100.0g
EUR 334.00
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Ala-OEt · HCl

F-2095.0250 250.0g
EUR 635.00
Description: Sum Formula: C5H11NO2·HCl; CAS# [17344-99-9] net

H-DL-Trp-NH2 · HCl

F-2155.0001 1.0g
EUR 115.00
Description: Sum Formula: C11H13N3O·HCl; CAS# [67607-61-8]

H-DL-Trp-NH2 · HCl

F-2155.0005 5.0g
EUR 176.00
Description: Sum Formula: C11H13N3O·HCl; CAS# [67607-61-8]

H-DL-Trp-OEt · HCl

F-2160.0025 25.0g
EUR 139.00
Description: Sum Formula: C13H16N2O2·HCl; CAS# [6519-67-1]

H-DL-Trp-OEt · HCl

F-2160.0100 100.0g
EUR 357.00
Description: Sum Formula: C13H16N2O2·HCl; CAS# [6519-67-1]

H-DL-Leu-NH2 · HCl

F-2360.0005 5.0g
EUR 115.00
Description: Sum Formula: C6H14N2O·HCl; CAS# [10466-60-1]

H-DL-Leu-NH2 · HCl

F-2360.0025 25.0g
EUR 284.00
Description: Sum Formula: C6H14N2O·HCl; CAS# [10466-60-1]

H-DL-Pro-NH2 · HCl

F-2385.0001 1.0g
EUR 115.00
Description: Sum Formula: C5H10N2O·HCl; CAS# [115630-49-4]

H-DL-Pro-NH2 · HCl

F-2385.0005 5.0g
EUR 261.00
Description: Sum Formula: C5H10N2O·HCl; CAS# [115630-49-4]

H-DL-Met-OMe · HCl

F-2535.0025 25.0g
EUR 126.00
Description: Sum Formula: C6H13NO2S·HCl; CAS# [16118-36-8]

H-DL-Met-OMe · HCl

F-2535.0100 100.0g
EUR 334.00
Description: Sum Formula: C6H13NO2S·HCl; CAS# [16118-36-8]

H-DL-Ser-OMe · HCl

F-2610.0025 25.0g
EUR 139.00
Description: Sum Formula: C4H9NO3·HCl; CAS# [5619-04-5]

H-DL-Ser-OMe · HCl

F-2610.0100 100.0g
EUR 368.00
Description: Sum Formula: C4H9NO3·HCl; CAS# [5619-04-5]

H-DL-Leu-OMe · HCl

F-2925.0025 25.0g
EUR 115.00
Description: Sum Formula: C7H15NO2·HCl; CAS# [6322-53-8]

H-DL-Leu-OMe · HCl

F-2925.0100 100.0g
EUR 284.00
Description: Sum Formula: C7H15NO2·HCl; CAS# [6322-53-8]

H-DL-Trp-OMe · HCl

F-3435.0005 5.0g
EUR 115.00
Description: Sum Formula: C12H14N2O2·HCl; CAS# [5619-09-0]

H-DL-Trp-OMe · HCl

F-3435.0025 25.0g
EUR 309.00
Description: Sum Formula: C12H14N2O2·HCl; CAS# [5619-09-0]

H-DL-Tyr-OMe · HCl

F-3600.0025 25.0g
EUR 115.00
Description: Sum Formula: C10H13NO3·HCl; CAS# [68697-61-0]

H-DL-Tyr-OMe · HCl

F-3600.0100 100.0g
EUR 368.00
Description: Sum Formula: C10H13NO3·HCl; CAS# [68697-61-0]

H-DL-Ala-bNA · HCl

K-1030.0001 1.0g
EUR 115.00
Description: Sum Formula: C13H14N2O·HCl; CAS# [74144-49-3]

H-DL-Ala-bNA · HCl

K-1030.0005 5.0g
EUR 297.00
Description: Sum Formula: C13H14N2O·HCl; CAS# [74144-49-3]

Bz-DL-Arg-bNA · HCl

K-1125.0001 1.0g
EUR 115.00
Description: Sum Formula: C23H25N5O2·HCl; CAS# [913-04-2]

Bz-DL-Arg-bNA · HCl

K-1125.0005 5.0g
EUR 176.00
Description: Sum Formula: C23H25N5O2·HCl; CAS# [913-04-2]

H-DL-Met-bNA · HCl

K-1435.0250 250.0mg
EUR 115.00
Description: Sum Formula: C15H18N2OS·HCl; CAS# [97405-58-8]

H-DL-Met-bNA · HCl

K-1435.1000 1.0g
EUR 200.00
Description: Sum Formula: C15H18N2OS·HCl; CAS# [97405-58-8]

Bz-DL-Arg-AMC · HCl

I-1075.0050 50.0mg
EUR 115.00
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

Bz-DL-Arg-AMC · HCl

I-1075.0250 250.0mg
EUR 309.00
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

Bz-DL-Arg-AMC · HCl

I-1075.1000 1.0g
EUR 866.00
Description: Sum Formula: C23H25N5O4·HCl; CAS# [102601-21-8]

Bz-DL-Arg-pNA · HCl

L-1140.0005 5.0g
EUR 115.00
Description: Sum Formula: C19H22N6O4·HCl; CAS# [911-77-3]

Bz-DL-Arg-pNA · HCl

L-1140.0025 25.0g
EUR 368.00
Description: Sum Formula: C19H22N6O4·HCl; CAS# [911-77-3]

H-DL-Asp(OMe)-OMe · HCl

F-1280.0025 25.0g
EUR 139.00
Description: Sum Formula: C6H11NO4·HCl; CAS# [14358-33-9]

H-DL-Asp(OMe)-OMe · HCl

F-1280.0100 100.0g
EUR 357.00
Description: Sum Formula: C6H11NO4·HCl; CAS# [14358-33-9]

H-DL-Asp(OMe)-OH · HCl

F-3240.0001 1.0g
EUR 115.00
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

H-DL-Asp(OMe)-OH · HCl

F-3240.0005 5.0g
EUR 273.00
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

H-DL-Asp(OMe)-OH · HCl

F-3240.0025 25.0g
EUR 998.00
Description: Sum Formula: C5H9NO4·HCl; CAS# [1835-52-5]

N-Me-DL-Phe-OMe · HCl

F-3545.0001 1.0g
EUR 273.00
Description: Sum Formula: C11H15NO2·HCl; CAS# [16975-45-4]

N-Me-DL-Phe-OMe · HCl

F-3545.0005 5.0g
EUR 998.00
Description: Sum Formula: C11H15NO2·HCl; CAS# [16975-45-4]

H-p-Chloro-DL-Phe-OMe · HCl

F-1455.0005 5.0g
EUR 200.00
Description: Sum Formula: C10H12ClNO2·HCl; CAS# [14173-40-1]

H-p-Chloro-DL-Phe-OMe · HCl

F-1455.0025 25.0g
EUR 683.00
Description: Sum Formula: C10H12ClNO2·HCl; CAS# [14173-40-1]

H-p-Fluoro-DL-Phe-OMe · HCl

F-1540.0001 1.0g
EUR 115.00
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-p-Fluoro-DL-Phe-OMe · HCl

F-1540.0005 5.0g
EUR 200.00
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-p-Fluoro-DL-Phe-OMe · HCl

F-1540.0025 25.0g
EUR 696.00
Description: Sum Formula: C10H12FNO2·HCl; CAS# [64282-12-8]

H-b-Chloro-DL-Ala-OH · HCl

F-2325.0001 1.0g
EUR 115.00
Description: Sum Formula: C3H6ClNO2·HCl; CAS# [35401-46-8]

H-b-Chloro-DL-Ala-OH · HCl

F-2325.0005 5.0g
EUR 309.00
Description: Sum Formula: C3H6ClNO2·HCl; CAS# [35401-46-8]

H-a-Me-DL-Phe-OMe · HCl

F-2805.0005 5.0g
EUR 273.00
Description: Sum Formula: C11H15NO2·HCl; CAS# [64665-60-7]

H-a-Me-DL-Phe-OMe · HCl

F-2805.0025 25.0g
EUR 998.00
Description: Sum Formula: C11H15NO2·HCl; CAS# [64665-60-7]

H-a-Me-DL-His-OH · 2 HCl

F-1795.0250 250.0mg
EUR 176.00
Description: Sum Formula: C7H11N3O2·2HCl; CAS# [32381-18-3]

H-a-Me-DL-His-OH · 2 HCl

F-1795.1000 1.0g
EUR 466.00
Description: Sum Formula: C7H11N3O2·2HCl; CAS# [32381-18-3]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O

F-2395.0050 50.0mg
EUR 115.00
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O

F-2395.0250 250.0mg
EUR 273.00
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-a-Difluoro-Me-DL-Orn-OH · HCl · H2O

F-2395.1000 1.0g
EUR 756.00
Description: Sum Formula: C6H12F2N2O2·HCl·H2O; CAS# [96020-91-6]

H-trans-4,5-Dehydro-DL-Lys-OH · 2 HCl

F-2970.0250 250.0mg
EUR 309.00
Description: Sum Formula: C6H12N2O2·2HCl; CAS# [39871-25-5] net

H-trans-4,5-Dehydro-DL-Lys-OH · 2 HCl

F-2970.1000 1.0g
EUR 866.00
Description: Sum Formula: C6H12N2O2·2HCl; CAS# [39871-25-5] net

H-DL-Ala-DL-Ala-OH

G-1140.0005 5.0g
EUR 176.00
Description: Sum Formula: C6H12N2O3; CAS# [2867-20-1]

H-DL-Ala-DL-Ala-OH

G-1140.0025 25.0g
EUR 611.00
Description: Sum Formula: C6H12N2O3; CAS# [2867-20-1]

H-DL-Leu-DL-Ala-OH

G-2470.0005 5.0g
EUR 126.00
Description: Sum Formula: C9H18N2O3; CAS# [5060-46-8]

H-DL-Leu-DL-Ala-OH

G-2470.0025 25.0g
EUR 418.00
Description: Sum Formula: C9H18N2O3; CAS# [5060-46-8]

DL-Penylalaninol

5-07735 5g Ask for price

DL-Penylalaninol

5-07736 25g Ask for price

DL-Phenylglycinol

5-07747 25g Ask for price

DL-Phenylglycinol

5-07748 100g Ask for price

DL-Prolinol

5-07763 5g Ask for price

DL-Prolinol

5-07764 25g Ask for price

DL-Aminoglutethimide

B2040-100
EUR 120.00

DL-Aminoglutethimide

B2040-500
EUR 262.00

DL-TBOA

B5084-10 10 mg
EUR 389.00
Description: Ki: 42 ?M for EAAT1; 5.7 ?M for EAAT2Glutamate acts as an excitatory neurotransmitter in the mammalian central nervous system and a potent neurotoxin.

DL-TBOA

B5084-50 50 mg
EUR 1476.00
Description: Ki: 42 ?M for EAAT1; 5.7 ?M for EAAT2Glutamate acts as an excitatory neurotransmitter in the mammalian central nervous system and a potent neurotoxin.

DL-Adrenaline

B1326-50 50 mg
EUR 128.00
Description: DL-Epinephrine(DL-Adrenaline) is a hormone and a neurotransmitter.

DL-AP4

B6200-100 100 mg
EUR 203.00

DL-AP7

B6203-10 10 mg
EUR 242.00

DL-AP7

B6203-50 50 mg
EUR 811.00

DL-AP5

B6204-10 10 mg
EUR 132.00

DL-AP5

B6204-25 25 mg
EUR 242.00

DL-AP5

B6204-50 50 mg
EUR 411.00

DL-Cystine

20-abx184678
  • EUR 551.00
  • EUR 300.00
  • EUR 203.00
  • 0
  • 1
  • 2
  • Shipped within 1-2 weeks.

DL-Isoleucine

20-abx184679
  • EUR 342.00
  • EUR 230.00
  • EUR 189.00
  • 0
  • 1
  • 2
  • Shipped within 1-2 weeks.

DL-Panthenol

20-abx184680
  • EUR 286.00
  • EUR 217.00
  • EUR 509.00
  • 0
  • 1
  • 2
  • Shipped within 1-2 weeks.

DL-Valine

20-abx185402
  • EUR 495.00
  • EUR 370.00
  • 0
  • 1
  • Shipped within 1-2 weeks.

DL-Lysine

20-abx185976
  • EUR 286.00
  • EUR 203.00
  • 0
  • 1
  • Shipped within 1-2 weeks.

DL-Dopa

abx187922-1000g 1000 g
EUR 718.00
  • Shipped within 1-2 weeks.

DL-Naproxen

20-abx182435
  • EUR 356.00
  • EUR 244.00
  • EUR 203.00
  • 0
  • 1
  • 2
  • Shipped within 1-2 weeks.

DL-Dithiothreitol

B7294-25000 25 g
EUR 299.00

DL-AP3

A4535-100 100 mg
EUR 197.00
Description: Competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.

DL-Dopa

HY-113404 10mM/1mL
EUR 113.00

DL-Carnitine

HY-B0399A 500mg
EUR 108.00

DL-Epinephrine

HY-B0447 500mg
EUR 108.00

DL-Panthenol

HY-B1024 10mM/1mL
EUR 113.00

DL-Xylose

HY-B1070 100mg
EUR 119.00

DL-Glutamine

HY-B1346 100mg
EUR 119.00

DL-Lysine

HY-B2236 1g
EUR 119.00

DL-Arginine

HY-N0454 100mg
EUR 108.00

DL-Borneol

HY-N1368 100mg
EUR 119.00

DL-TBOA

HY-107522 10mM/1mL
EUR 563.00

DL-Pantolactone

GX6080-10G 10 g
EUR 50.00

DL-Pantolactone

GX6080-25G 25 g
EUR 61.00

DL-Cycloserine

F-1485.0050 50.0mg
EUR 212.00
Description: Sum Formula: C3H6N2O2; CAS# [68-39-3]

DL-Cycloserine

F-1485.0250 250.0mg
EUR 756.00
Description: Sum Formula: C3H6N2O2; CAS# [68-39-3]

DL-Cycloserine

F-1485.1000 1.0g
EUR 2207.00
Description: Sum Formula: C3H6N2O2; CAS# [68-39-3]

DL-Thyronine

F-2405.0001 1.0g
EUR 212.00
Description: Sum Formula: C15H15NO4; CAS# [1034-10-2]

DL-Thyronine

F-2405.0005 5.0g
EUR 756.00
Description: Sum Formula: C15H15NO4; CAS# [1034-10-2]

DL-Menthol

GL0768-100G 100 g
EUR 60.00

DL-Menthol

GL0768-250G 250 g
EUR 83.00

DL-Thiorphan

GL2922-25MG 25 mg
EUR 253.00

DL-Thiorphan

GL2922-5MG 5 mg
EUR 102.00

DL-Tryptophan

GM0325-100G 100 g
EUR 174.00

DL-Tryptophan

GM0325-25G 25 g
EUR 78.00

DL-Tryptophan

GM0325-5G 5 g
EUR 46.00

DL-Homoserine

GM0565-1G 1 g
EUR 62.00

DL-Homoserine

GM0565-5G 5 g
EUR 123.00

DL-Isoleucine

GM0912-100G 100 g
EUR 174.00

DL-Isoleucine

GM0912-10G 10 g
EUR 50.00

DL-Isoleucine

GM0912-25G 25 g
EUR 78.00

DL-Isoleucine

GM0912-50G 50 g
EUR 110.00

DL-Isoleucine

GM0912-5G 5 g
EUR 46.00

DL-Norleucine

GM0955-100G 100 g
EUR 150.00

DL-Norleucine

GM0955-25G 25 g
EUR 70.00

DL-Methionine

GM2607-100G 100 g
EUR 44.00

DL-Methionine

GM2607-1KG 1 kg
EUR 94.00

DL-Methionine

GM2607-250G 250 g
EUR 53.00

DL-Methionine

GM2607-500G 500 g
EUR 66.00

DL-Methionine

GM2607-5KG 5 kg
EUR 229.00

DL-Valine

GM3274-100G 100 g
EUR 66.00

DL-Valine

GM3274-1KG 1 kg
EUR 261.00

DL-Valine

GM3274-250G 250 g
EUR 102.00

DL-Valine

GM3274-25G 25 g
EUR 46.00

DL-Valine

GM3274-500G 500 g
EUR 158.00

DL-Alanine

GM4363-100G 100 g
EUR 46.00

DL-Alanine

GM4363-1KG 1 kg
EUR 102.00

DL-Alanine

GM4363-250G 250 g
EUR 53.00

DL-Alanine

GM4363-25G 25 g
EUR 40.00

DL-Alanine

GM4363-500G 500 g
EUR 70.00

DL-Alanine

GM4363-5KG 5 kg
EUR 281.00

DL-Cystine

GM5088-1G 1 g
EUR 62.00

DL-Cystine

GM5088-5G 5 g
EUR 126.00

DL-Phenylalanine

GM5287-100G 100 g
EUR 78.00

DL-Phenylalanine

GM5287-1KG 1 kg
EUR 261.00

DL-Phenylalanine

GM5287-250G 250 g
EUR 110.00

DL-Phenylalanine

GM5287-25G 25 g
EUR 50.00

DL-Phenylalanine

GM5287-500G 500 g
EUR 166.00

DL-Histidine

GM6216-100G 100 g
EUR 245.00

DL-Histidine

GM6216-25G 25 g
EUR 110.00

DL-Histidine

GM6216-5G 5 g
EUR 58.00

DL-Cysteine

GM6393-1G 1 g
EUR 54.00

DL-Tyrosine

GM6469-100G 100 g
EUR 150.00

DL-Tyrosine

GM6469-10G 10 g
EUR 50.00

DL-Tyrosine

GM6469-250G 250 g
EUR 269.00

DL-Tyrosine

GM6469-25G 25 g
EUR 70.00

DL-Tyrosine

GM6469-50G 50 g
EUR 102.00

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