Two novel CLN6 mutations in variant late-infantile neuronal ceroid lipofuscinosis patients of Turkish origin.

lipofuscinoses neuronal ceroid (NCLs) is the most common neurodegenerative disorder-onset period marked by autosomal recessive inheritance, epileptic seizures, progressive psychomotor damage, visual failure, and early death. At least seven subtypes of NCLs time-onset have been identified from which the final form of infantile-onset (LINCLs) is genetically most heterogeneous with four genes that underlie identified.

A variant form of LINCL (vLINCL) present in patients Turkey has been regarded as a clinical entity and different genetic (CLN7). However, we have recently demonstrated that mutations in the gene CLN8 account for a subset of Turkey vLINCL. Towards identifying genes CLN7 us here filtered NCL loci known homozygosity in a family of nine Turkish vLINCL.

This locus is issued in seven families who may represent the ‘true’ Turkish vLINCL. In two families, we identified two novel homozygous mutation in the gene CLN6: base substitution intronic (c.542 + 5G> T) affects splicing of the transcript and nonsense mutation (c.663C> G) creates a stop codon at Tyrosine 221. These data indicate that CLN6 mutations, other than those of CLN8, should be considered as a diagnostic alternative in patients Turkey vLINCL. The genetic background of the ‘true’ Turkish vLINCL, CLN7, still to be defined.

di-Sodium Dihydrogen Ethylenediaminetetraacetate Dihydrate
15130-95	NACALAI TESQUE	500G	EUR 50.4

di-Sodium Dihydrogen Ethylenediaminetetraacetate Dihydrate
09592-45	NACALAI TESQUE	500G	EUR 67.2

Disodium Zinc Ethylenediaminetetraacetate Tetrahydrate
D493658	Toronto Research Chemicals	100g	EUR 121

Calcium di-Sodium Ethylenediaminetetraacetate
15116-82	NACALAI TESQUE	25G	EUR 14

di-Sodium Zinc Ethylenediaminetetraacetate
15126-52	NACALAI TESQUE	25G	EUR 13.3

EDTA, Disodium Salt, Dihydrate, (Ethylenediaminetetraacetic Acid), 1kg
PC0706-1kg	Vivantis	each	Ask for price

EDTA, Disodium Salt, Dihydrate, (Ethylenediaminetetraacetic Acid), 500g
PC0706-500g	Vivantis	each	Ask for price

Copper(Ⅱ) di-Sodium Ethylenediaminetetraacetate
15119-52	NACALAI TESQUE	25G	EUR 18.9

Manganese(Ⅱ) di-Sodium Ethylenediaminetetraacetate
15123-82	NACALAI TESQUE	25G	EUR 88.2

Ethylenediaminetetraacetic acid disodium salt dihydrate Reagent Grade
E08850	Pfaltz & Bauer	100G	EUR 119.52
Description: CAS N° 139-33-3

Magnesium di-Sodium Ethylenediaminetetraacetate Tetrahydrate
15122-92	NACALAI TESQUE	25G	EUR 15.4

di-Potassium Dihydrogen Ethylenediaminetetraacetate
15108-05	NACALAI TESQUE	500G	EUR 81.2

di-Potassium Dihydrogen Ethylenediaminetetraacetate
15108-92	NACALAI TESQUE	25G	EUR 12.46

0.1mol/l-di-Sodium Dihydrogen Ethylenediaminetetraacetate Solution
37310-55	NACALAI TESQUE	500ML	EUR 18.9

0.01mol/l-di-Sodium Dihydrogen Ethylenediaminetetraacetate Solution
37311-45	NACALAI TESQUE	500ML	EUR 18.9

0.2mol/l-di-Sodium Dihydrogen Ethylenediaminetetraacetate Solution
37336-35	NACALAI TESQUE	500ML	EUR 25.9

0.02mol/l-di-Sodium Dihydrogen Ethylenediaminetetraacetate Solution
37337-25	NACALAI TESQUE	500ML	EUR 19.6

0.05mol/l-di-Sodium Dihydrogen Ethylenediaminetetraacetate Solution
37341-55	NACALAI TESQUE	500ML	EUR 19.6

tetra-Sodium Ethylenediaminetetraacetate
15114-02	NACALAI TESQUE	25G	EUR 13.3

tetra-Sodium Ethylenediaminetetraacetate
15114-15	NACALAI TESQUE	500G	EUR 35.7

Iron(Ⅲ) Monosodium Ethylenediaminetetraacetate
15120-12	NACALAI TESQUE	25G	EUR 15.4

Iron(Ⅲ) Monosodium Ethylenediaminetetraacetate
15120-25	NACALAI TESQUE	500G	EUR 48.65

tri-Sodium Hydrogen Ethylenediaminetetraacetate
15113-12	NACALAI TESQUE	25G	EUR 10.85

tri-Sodium Hydrogen Ethylenediaminetetraacetate
15113-25	NACALAI TESQUE	500G	EUR 65.8

Ethylenediaminetetraacetic Acid Disodium Salt
E918335	Toronto Research Chemicals	100g	EUR 69
Description: 139-33-3

tri-Potassium Hydrogen Ethylenediaminetetraacetate
15109-82	NACALAI TESQUE	25G	EUR 22.4

Ethylenediaminetetraacetic acid trisodium salt dihydrate 98%
E08540	Pfaltz & Bauer	100G	EUR 140
Description: CAS N° 150-38-9

Ethylenediaminetetraacetic Acid Tetrasodium Salt Dihydrate
E918310	Toronto Research Chemicals	100g	EUR 57
Description: 10378-23-1

Ethylenediaminetetraacetic acid manganese disodium salt trihydrate
20-abx184692	Abbexa	Ask for price Ask for price	100 g 500 g

Ethylenediaminetetraacetic Acid
15105-22	NACALAI TESQUE	25G	EUR 23.1

Ethylenediaminetetraacetic Acid
15105-35	NACALAI TESQUE	500G	EUR 46.9

Ethylenediaminetetraacetic Acid
15107-02	NACALAI TESQUE	25G	EUR 25.55

Ethylenediamine-N,N,N’,N’-tetraacetic Acid Disodium Dihydrate
E917735	Toronto Research Chemicals	10g	EUR 253
Description: 6381-92-6

Ethylenediaminetetraacetic-d12 Acid
E917746	Toronto Research Chemicals	10mg	EUR 64
Description: 203806-08-0

Ethylenediaminetetraacetic Acid-d16
E917751	Toronto Research Chemicals	10mg	EUR 75
Description: 203805-96-3

Ethylenediaminetetraacetic Acid Dianhydride
E917595	Toronto Research Chemicals	10g	EUR 58
Description: 23911-25-3

Ethylenediaminetetraacetic Acid Dilithium Salt
E918318	Toronto Research Chemicals	10g	EUR 800
Description: 14531-56-7

Ethylenediaminetetraacetic acid (trisodium salt)
HY-B1009	MedChemExpress	1g	EUR 43.29
Description: Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research[1][2][3][4][5][6][7].

Ethylenediaminetetraacetic acid trisodium salt
T0423-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Ethylenediaminetetraacetic acid trisodium salt

Ethylenediaminetetraacetic acid trisodium salt
T0423-1g	TargetMol Chemicals	1g	Ask for price
Description: Ethylenediaminetetraacetic acid trisodium salt

Ethylenediaminetetraacetic acid trisodium salt
T0423-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Ethylenediaminetetraacetic acid trisodium salt

Ethylenediaminetetraacetic acid trisodium salt
T0423-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Ethylenediaminetetraacetic acid trisodium salt

Ethylenediaminetetraacetic acid trisodium salt
T0423-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Ethylenediaminetetraacetic acid trisodium salt

Ethylenediaminetetraacetic acid trisodium salt solution
MBS576716-1g	MyBiosource	1g	EUR 145

Ethylenediaminetetraacetic acid trisodium salt solution
MBS576716-500mg	MyBiosource	500mg	EUR 145

Ethylenediaminetetraacetic acid trisodium salt solution
MBS576716-5x1g	MyBiosource	5x1g	EUR 505

(S)-1-(p-Bromoacetamidobenzyl)ethylenediaminetetraacetic Acid (~80%)
B679000	Toronto Research Chemicals	25mg	EUR 193
Description: 81677-64-7

rac (Aminomethyl)ethylenediaminetetraacetic Acid tetra-(t-Butyl Ester)
A616160	Toronto Research Chemicals	250mg	EUR 201
Description: 1391052-55-3

4-Aminobenzyl Ethylenediaminetetraacetic Acid, Tetra(t-butyl) Ester
MBS6078540-10mg	MyBiosource	10(mg	EUR 505

4-Aminobenzyl Ethylenediaminetetraacetic Acid, Tetra(t-butyl) Ester
MBS6078540-5x10mg	MyBiosource	5x10mg	EUR 2125

rac (Aminomethyl)ethylenediaminetetraacetic Acid tetra-(t-Butyl Ester)
MBS6034066-25mg	MyBiosource	25(mg	EUR 610

rac (Aminomethyl)ethylenediaminetetraacetic Acid tetra-(t-Butyl Ester)
MBS6034066-5x25mg	MyBiosource	5x25mg	EUR 2600

(S)-1-(p-Bromoacetamidobenzyl)ethylenediaminetetraacetic Acid (BABE)
MBS6041271-5mg	MyBiosource	5(mg	EUR 545

(S)-1-(p-Bromoacetamidobenzyl)ethylenediaminetetraacetic Acid (BABE)
MBS6041271-5x5mg	MyBiosource	5x5(mg	EUR 2310

(S)-1-(4-Aminoxyacetamidobenzyl)ethylenediaminetetraacetic Acid (AABE)
MBS6025607-5mg	MyBiosource	5(mg	EUR 545

(S)-1-(4-Aminoxyacetamidobenzyl)ethylenediaminetetraacetic Acid (AABE)
MBS6025607-5x5mg	MyBiosource	5x5(mg	EUR 2310

EDTA Iron(III) sodium salt (Ethylenediaminetetraacetic acid iron(III), Edathamil, Komplexon II)
MBS635476-50g	MyBiosource	50g	EUR 345

EDTA Iron(III) sodium salt (Ethylenediaminetetraacetic acid iron(III), Edathamil, Komplexon II)
MBS635476-5x50g	MyBiosource	5x50g	EUR 1410

4-(N-Boc-aminoxyacetamido)benzyl Ethylenediaminetetraacetic Acid, Tetra(t-butyl) Ester
MBS6118728-5mg	MyBiosource	5(mg	EUR 525

4-(N-Boc-aminoxyacetamido)benzyl Ethylenediaminetetraacetic Acid, Tetra(t-butyl) Ester
MBS6118728-5x5mg	MyBiosource	5x5(mg	EUR 2210

Ethylenediaminetetra(methylenephosphonic acid)
E918323	Toronto Research Chemicals	5g	EUR 76

Ethylenediamine-N,N,N’,N’-tetraacetic Acid Calcium Disodium Hydrate
E917590	Toronto Research Chemicals	100g	EUR 161
Description: 23411-34-9

Ethylenediamine dihydroiodide
E08440	Pfaltz & Bauer	500G	EUR 2053.6
Description: CAS N° 5700-49-2

Ethylenediamine Dihydrochloride
15129-22	NACALAI TESQUE	25G	EUR 16.8

Ethylenediamine dihydrochloride
40000027-1	Bio-WORLD	100 g	EUR 29.69

Ethylenediamine dihydrochloride
40000027-2	Bio-WORLD	500 g	EUR 98.98

Ethylenediamine dihydrochloride
GK6724	Glentham Life Sciences	100g	EUR 29.04

Ethylenediamine dihydrochloride
GK6724-100	Glentham Life Sciences	100	EUR 23.8

Ethylenediamine dihydrochloride
GK6724-100G	Glentham Life Sciences	100 g	EUR 64.8

Ethylenediamine dihydrochloride
GK6724-250	Glentham Life Sciences	250	EUR 55.4

Ethylenediamine dihydrochloride
GK6724-250G	Glentham Life Sciences	250 g	EUR 103.2

Ethylenediamine dihydrochloride
GK6724-500	Glentham Life Sciences	500	EUR 87.1

Ethylenediamine dihydrochloride
GK6724-500G	Glentham Life Sciences	500 g	EUR 141.6

Ethylenediamine Dihydrochloride
E918353	Toronto Research Chemicals	10g	EUR 69
Description: 333-18-6

N-(1-Naphthyl)ethylenediamine dihydrochl
RM1073-25G	EWC Diagnostics	1 unit	EUR 69.21
Description: N-(1-Naphthyl)ethylenediamine dihydrochl

N-(1-Naphthyl)ethylenediamine dihydrochl
RM1073-5G	EWC Diagnostics	1 unit	EUR 15.42
Description: N-(1-Naphthyl)ethylenediamine dihydrochl

N-(1-Naphthyl)ethylenediamine dihydrochloride
GK9342	Glentham Life Sciences	5g	EUR 195.68

N-(1-Naphthyl)ethylenediamine dihydrochloride
GK9342-100	Glentham Life Sciences	100	EUR 213.7

N-(1-Naphthyl)ethylenediamine dihydrochloride
GK9342-100G	Glentham Life Sciences	100 g	EUR 294

N-(1-Naphthyl)ethylenediamine dihydrochloride
GK9342-25	Glentham Life Sciences	25	EUR 79.1

N-(1-Naphthyl)ethylenediamine dihydrochloride
GK9342-25G	Glentham Life Sciences	25 g	EUR 132

N-(1-Naphthyl)ethylenediamine dihydrochloride
GK9342-5	Glentham Life Sciences	5	EUR 23.8

N-(1-Naphthyl)ethylenediamine dihydrochloride
GK9342-5G	Glentham Life Sciences	5 g	EUR 64.8

N-(1-Naphthyl)-ethylenediamine dihydrochloride
NB0650	Bio Basic	10g	EUR 84.01

Ethylenediamine dihydrochloride_x000D__x000D__x000D_
E08430	Pfaltz & Bauer	5G	EUR 436.97
Description: CAS N° 333-18-6

CTP disodium dihydrate
561576	MedKoo Biosciences	100.0mg	EUR 250

CTP disodium dihydrate
MBS5758743-100mg	MyBiosource	100mg	EUR 320

CTP disodium dihydrate
MBS5758743-10mg	MyBiosource	10mg	EUR 160

CTP disodium dihydrate
MBS5758743-25mg	MyBiosource	25mg	EUR 200

CTP disodium dihydrate
MBS5758743-50mg	MyBiosource	50mg	EUR 250

CTP disodium dihydrate
MBS5758743-5mg	MyBiosource	5mg	EUR 145

CTP disodium dihydrate
MBS3611149-5mg	MyBiosource	5mg	EUR 200

CTP disodium dihydrate
MBS3611149-5x5mg	MyBiosource	5x5mg	EUR 580

CTP disodium dihydrate
T7881-10mg	TargetMol Chemicals	10mg	Ask for price
Description: CTP disodium dihydrate

CTP disodium dihydrate
T7881-1g	TargetMol Chemicals	1g	Ask for price
Description: CTP disodium dihydrate

CTP disodium dihydrate
T7881-1mg	TargetMol Chemicals	1mg	Ask for price
Description: CTP disodium dihydrate

CTP disodium dihydrate
T7881-50mg	TargetMol Chemicals	50mg	Ask for price
Description: CTP disodium dihydrate

CTP disodium dihydrate
T7881-5mg	TargetMol Chemicals	5mg	Ask for price
Description: CTP disodium dihydrate

N-(1-Naphthyl)Ethylenediamine Dihydrochloride (NEDA) extrapure AR, ACS, 98%
61166	Sisco Laboratories	5 Gms	EUR 5.78
Description: Part B

CTP Disodium Dihydrate (>85%)
C831028	Toronto Research Chemicals	100mg	EUR 221
Description: 81012-87-5

Balsalazide Disodium Dihydrate
B116295	Toronto Research Chemicals	10mg	EUR 431
Description: 150399-21-6

E.D.T.A., disodium salt, dihydrate
MB011-1KG	EWC Diagnostics	1 unit	EUR 26.7
Description: E.D.T.A., disodium salt, dihydrate

E.D.T.A., disodium salt, dihydrate
MB011-500G	EWC Diagnostics	1 unit	EUR 15.27
Description: E.D.T.A., disodium salt, dihydrate

E.D.T.A., disodium salt dihydrate
PCT0105-100G	EWC Diagnostics	1 unit	EUR 6.93
Description: E.D.T.A., disodium salt dihydrate

E.D.T.A., disodium salt dihydrate
PCT0105-1KG	EWC Diagnostics	1 unit	EUR 31.97
Description: E.D.T.A., disodium salt dihydrate

E.D.T.A., disodium salt dihydrate
PCT0105-500G	EWC Diagnostics	1 unit	EUR 17.75
Description: E.D.T.A., disodium salt dihydrate

E.D.T.A., disodium salt dihydrate
PCT0105-5KG	EWC Diagnostics	1 unit	EUR 127.76
Description: E.D.T.A., disodium salt dihydrate

ADP disodium salt, dihydrate
MB191-1G	EWC Diagnostics	1 unit	EUR 14.92
Description: ADP disodium salt, dihydrate

ADP disodium salt, dihydrate
MB191-5G	EWC Diagnostics	1 unit	EUR 72.95
Description: ADP disodium salt, dihydrate

Nitroprusside (disodium dihydrate)
HY-A0119	MedChemExpress	500mg	EUR 59.52
Description: Nitroprusside disodium dehydrate (Sodium nitroprusside dihydrate) is a vasodilator that available for the research of acute hypertension, heart failure. Nitroprusside disodium dehydrate induces autophagy in glutathione-depleted osteoblasts. Nitroprusside disodium dehydrate acts as a nitric oxide (NO) donor in a rat intestinal ischemia reperfusion model[1][2][3][4].

Nitroprusside disodium dihydrate
T6991-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Nitroprusside disodium dihydrate

Nitroprusside disodium dihydrate
T6991-1g	TargetMol Chemicals	1g	Ask for price
Description: Nitroprusside disodium dihydrate

Nitroprusside disodium dihydrate
T6991-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Nitroprusside disodium dihydrate

Nitroprusside disodium dihydrate
T6991-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Nitroprusside disodium dihydrate

Nitroprusside disodium dihydrate
T6991-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Nitroprusside disodium dihydrate

EDTA Disodium Salt Dihydrate
40500012-1	Bio-WORLD	500 g	EUR 69.53

EDTA Disodium Salt Dihydrate
40500012-2	Bio-WORLD	1 kg	EUR 114.8

EDTA Disodium Salt Dihydrate
40500012-3	Bio-WORLD	2.5 kg	EUR 241.35

EDTA Disodium Salt Dihydrate
40500012-4	Bio-WORLD	5 kg	EUR 411.26

EDTA Disodium Salt Dihydrate
40500012-5	Bio-WORLD	10 kg	EUR 800.11

EDTA, Disodium Dihydrate Salt
20-147	Genesee Scientific	500g/Unit	EUR 73.04
Description: Ultra Pure Grade

EDTA, Disodium Salt, Dihydrate
A2503-1KG	Biomatik Corporation	1KG	EUR 46.2
Description: Biotechnology

EDTA, Disodium Salt, Dihydrate
A2503-500G	Biomatik Corporation	500G	EUR 26.4
Description: Biotechnology

EDTA, Disodium Salt, Dihydrate
A2503-5KG	Biomatik Corporation	5KG	EUR 189.2
Description: Biotechnology

EDTA, Disodium Salt, Dihydrate
CH032	ABM	500 g	EUR 195.6

EDTA, Disodium Salt, Dihydrate
CH033	ABM	1.0 kg	EUR 130
Description: A reversible metalloprotease inhibitor useful for chelating metal ions.

EDTA, Disodium Salt, Dihydrate
CH034	ABM	2.5 kg	EUR 400.8

EDTA disodium salt dihydrate
GE3023	Glentham Life Sciences	100g	EUR 108.65

EDTA disodium salt dihydrate
GE3023-1	Glentham Life Sciences	1	EUR 39.4

EDTA disodium salt dihydrate
GE3023-100	Glentham Life Sciences	100	EUR 11.3

EDTA disodium salt dihydrate
GE3023-100G	Glentham Life Sciences	100 g	EUR 48

EDTA disodium salt dihydrate
GE3023-1KG	Glentham Life Sciences	1 kg	EUR 84

EDTA disodium salt dihydrate
GE3023-250	Glentham Life Sciences	250	EUR 15.9

EDTA disodium salt dihydrate
GE3023-250G	Glentham Life Sciences	250 g	EUR 55.2

EDTA disodium salt dihydrate
GE3023-5	Glentham Life Sciences	5	EUR 118.7

EDTA disodium salt dihydrate
GE3023-500	Glentham Life Sciences	500	EUR 23.8

EDTA disodium salt dihydrate
GE3023-500G	Glentham Life Sciences	500 g	EUR 64.8

EDTA disodium salt dihydrate
GE3023-5KG	Glentham Life Sciences	5 kg	EUR 180

EDTA, disodium salt, dihydrate
EB0185	Bio Basic	500g	EUR 84.01

EDTA disodium salt dihydrate
GRM1195-100G	EWC Diagnostics	1 unit	EUR 6.93
Description: EDTA disodium salt dihydrate

EDTA disodium salt dihydrate
GRM1195-1KG	EWC Diagnostics	1 unit	EUR 25.12
Description: EDTA disodium salt dihydrate

EDTA disodium salt dihydrate
GRM1195-500G	EWC Diagnostics	1 unit	EUR 13.97
Description: EDTA disodium salt dihydrate

EDTA Disodium Salt Dihydrate
MBS635343-100g	MyBiosource	100g	EUR 155

EDTA Disodium Salt Dihydrate
MBS635343-1kg	MyBiosource	1kg	EUR 320

EDTA Disodium Salt Dihydrate
MBS635343-25kg	MyBiosource	2.5kg	EUR 690

EDTA Disodium Salt Dihydrate
MBS635343-500g	MyBiosource	500g	EUR 260

EDTA Disodium Salt Dihydrate
MBS635343-5kg	MyBiosource	5kg	EUR 1020

EDTA, Disodium Salt, Dihydrate
MBS4156372-500g	MyBiosource	500g	EUR 260

EDTA, Disodium Salt, Dihydrate
MBS4156372-5x500g	MyBiosource	5x500g	EUR 920

EDTA, Disodium Salt, Dihydrate
MBS4156373-1kg	MyBiosource	1kg	EUR 285

EDTA, Disodium Salt, Dihydrate
MBS4156373-5x1kg	MyBiosource	5x1kg	EUR 1095

EDTA, Disodium Salt, Dihydrate
MBS4156374-25kg	MyBiosource	2.5kg	EUR 465

EDTA, Disodium Salt, Dihydrate
MBS4156374-5x25kg	MyBiosource	5x2.5kg	EUR 1705

EDTA Disodium Salt Dihydrate 0.057M
40500040-1	Bio-WORLD	500 mL	EUR 25.2

EDTA Disodium Salt Dihydrate 0.057M
40500040-2	Bio-WORLD	1 L	EUR 42.6

EDTA Disodium Salt Dihydrate 0.057M
40500040-3	Bio-WORLD	4 L	EUR 110.75

Disodium Molybdate(Ⅵ) Dihydrate
31621-52	NACALAI TESQUE	25G	EUR 12.25

Disodium Molybdate(Ⅵ) Dihydrate
31621-65	NACALAI TESQUE	500G	EUR 88.2

Tartaric acid disodium dihydrate
C6836-1000	ApexBio	1g	EUR 48
Description: Metabolic Enzyme/Protease|Phosphatase

Tartaric acid disodium dihydrate
C6836-500	ApexBio	500mg	EUR 40
Description: Metabolic Enzyme/Protease|Phosphatase